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Search Result

Search Results for " ox2r "

Targets

OX Receptor

13

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3177 Orexin 2 Receptor Agonist OX2R OX Receptor
Orexin 2 Receptor Agonist (OX2R) is an effective (EC50: 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio: 70) agonist.
T62855 OX2R-IN-1
OX2R-IN-1 is an OX2R antagonist (a potential OX2R binding agent) that exhibits low cytotoxicity (IC50: 484 μM). oX2R-IN-1 has blood-brain barrier permeability and a short drug half-life.
T3722 MK-1064 Urokinase inhibitor 1,MK 1064 OX Receptor
MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).
T39229 YNT-185 OX Receptor
YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R, respectively. Furthermore, YNT-185 effectively alleviates symptoms of ...
T12877L Seltorexant JNJ-42847922 OX Receptor
Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human a...
T5503 IPSU OX Receptor
IPSU is an antagonist of OX2 receptor. IPSU Exhibits approximately six-fold selectivity for OX2 versus OX1 receptors.
T4965 TCS-OX2-29 OX Receptor
TCS-OX2-29 is a potent and selective OX2 receptor antagonist (IC50: 40 nM). It displays >250-fold selectivity for OX2 over OX1.
T12877 Seltorexant hydrochloride JNJ-42847922 hydrochloride Others
Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.
T62050 Orexin receptor antagonist 4
Orexin receptor antagonist 4 is potent and selective orexin 2 receptor (OX2R) antagonist. Orexin receptor antagonist 4 shows IC50 of 4.27 nM and 295 nM for OX2R and OX1R, respectively.
T39808 Firazorexton
Firazorexton is a potent orexin type 2 receptor (OX2R) agonist.
T24013 DORA 42 DORA42,DORA-42
DORA 42 is a dual antagonist of the orexin receptor OX1R and OX2R.
T39004 Vornorexant ORN-0829,TS-142
Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC 50 values of 1.05 nM and 1.27 nM, respectively. Vornorexant exhibits potent sleep-promoting effects in vivo and can be used for insomnia tr...
T78636 Firazorexton hydrate TAK-994
Firazorexton hydrate (TAK-994) is a brain-penetrant and orally active agonist of the orexin type 2 receptor (OX2R) with a potent EC50 of 19 nM. It effectively reduces wakefulness fragmentation and cataplexy-like episodes...

Recombinant Proteins

Species：
Human (6)
Mouse (2)
Cynomolgus (1)
Expression System：
HEK293 Cells (9)
Tag：
C-His-Avi (2)
His (2)
His, hFc (2)
C-6xHis (1)
C-His (1)
C-hFc (1)
Cat No. Product Name Species Expression System
TMPY-01302 CD200R Protein, Human, Recombinant (His) Human HEK293 Cells
CD200R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.2 kDa and the accession number is B7ZKV2.
TMPY-01665 CD200R Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD200R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.6 kDa and the accession number is Q9ES57.
TMPY-01092 CD200R Protein, Mouse, Recombinant (His & hFc) Mouse HEK293 Cells
CD200R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 51.3 kDa and the accession number is Q9ES57.
TMPY-01261 CD200R Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
CD200R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 54.9 kDa and the accession number is B7ZKV2.
TMPK-00624 CD200R1/CRTR2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-00622 CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-00623 CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPK-01262 CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid...
TMPJ-00233 CD200R1/CRTR2 Protein, Human, Recombinant (His) Human HEK293 Cells
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ...
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