Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 52.00 | |
5 mg | 5 days | $ 89.00 | |
10 mg | 5 days | $ 152.00 | |
1 mL * 10 mM (in DMSO) | 5 days | $ 98.00 |
Description | Seltorexant hydrochloride is a selective, orally active and high-affinity antagonist of OX2R with pKi values of 8.0 and 8.1 for human and rat OX2R. |
Targets&IC50 | OX2R (human):8.0 (pki), OX2R (rat):8.1 (pki) |
In vivo | Seltorexant hydrochloride (JNJ-42847922 hydrochloride) (3-30 mg/kg; p.o.) dose-dependently induces and prolongs sleep in male Sprague-Dawley rats. The sleep-promoting effects of Seltorexant hydrochloride (30 mg/kg; p.o.; per day for 7 days) are maintained upon 7-day repeated dosing in rats. |
Synonyms | JNJ-42847922 hydrochloride |
Molecular Weight | 443.91 |
Formula | C21H23ClFN7O |
CAS No. | 1293284-49-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 83.33 mg/mL (187.72 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Seltorexant hydrochloride 1293284-49-7 Others Seltorexant Hydrochloride JNJ-42847922 hydrochloride JNJ 42847922 Hydrochloride JNJ-42847922 Hydrochloride JNJ42847922 Hydrochloride inhibitor inhibit