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Search Results for " nox2 "

14

Compounds

Cat No. Product Name Synonyms Targets
T81647 NOX2-IN-2
NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM. It effectively suppresses reactive oxygen species (ROS) pro...
T81648 NOX2-IN-1
NOX2-IN-1 (compound 10) serves as an inhibitor of the enzyme nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2). It specifically disrupts the p47phox-p22phox protein-protein interaction, exhibiting high...
T22990 ML-090 Fluoflavine NADPH-oxidase , Others
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
T10353 APX-115 free base Ewha-18278 free base NADPH-oxidase , NADPH
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid...
T10354 APX-115 Ewha-18278 NADPH-oxidase
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
T25952 Phox-I2 Phox I2,PhoxI2 NADPH-oxidase
Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
TN3016 4',6,7-Trimethoxyisoflavone MMP
4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation.
TP1886L1 NoxA1ds acetate(1435893-78-9 free base) NADPH-oxidase
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col...
T15433 GSK2795039 Apoptosis , Reactive Oxygen Species , ROS , NADPH
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).
T8107 GLX351322 NADPH-oxidase , NADPH
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T25951 Phox-I1 Phox I1
Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.
T75949 NoxA1ds TFA
NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1), with an inhibition concentration (IC50) of 20 nM, demonstrating selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits ...
T62004 (Rac)-Nebivolol
(Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective antagonist of β1-adrenergic receptor (IC 50= 0.8 nM). Nebivolol shows Vasodilatory activity. In the early stages of ethanol-ind...
TP1886 NoxA1ds
Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Atte...
TargetMol