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Search Result

Search Results for " neuropeptide y "

Targets

Neuropeptide Y Receptor Neuropeptide Y Receptor

85

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1140L Neuropeptide Y (29-64), amide, human acetate Neuropeptide Y Receptor
Neuropeptide Y (29-64), amide, human acetate is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
TP2206 [Leu31,Pro34]-Neuropeptide Y (porcine) Neuropeptide Y Receptor
High affinity neuropeptide Y Y1 receptor agonist
TP2194L Neuropeptide Y (scrambled) Acetate Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate Others
Neuropeptide Y (scrambled) Acetate (Pro-Neuropeptide Y (scrambled) Acetate) is a scrambled peptide of Neuropeptide Y that has been implicated in Alzheimer's disease (AD) and may have neuroprotective effects.
TP1984L [D-Trp34]-Neuropeptide Y Acetate [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base) Neuropeptide Y Receptor
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-...
T36446 Neuropeptide Y (human) (TFA)
Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.
T36447 Neuropeptide Y 13-36 (porcine)
Neuropeptide Y 13-36 (porcine) is a selective neuropeptide Y2 receptor agonist.
T36445 Neuropeptide Y (3-36) (human, rat)
Neuropeptide Y (3-36) (human, rat) is a metabolite of neuropeptide Y (NPY) generated by dipeptidyl peptidase-4 (DPP4). Known as a selective Y2 receptor agonist, Neuropeptide Y (3-36) (human, rat) effectively reduces the ...
TP1140 Neuropeptide Y (human) Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human
Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.
TP2194 Neuropeptide Y (scrambled) Others
Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiologi...
TP1984 [D-Trp34]-Neuropeptide Y
Potent neuropeptide Y (NPY) Y5 receptor agonist (pEC50 values are 7.82, 6.28, 6.44 and > 6 at rat Y5, Y4, Y1 and Y2 receptors respectively) that displays > 26-fold, > 1000-fold and > 1000-fold selectivity over Y1, Y2 and...
TP1818 Neuropeptide Y(29-64)
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.
TP1681 Neuropeptide Y (22-36)
Neuropeptide Y (22-36), a 15 amino acid peptide, is a fragment of Neuropeptide Y.Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the centra...
T35599 Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced ...
TP1081 Neuropeptide Y (13-36), amide, human Neuropeptide Y (13-36), human
Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
TP1985 [Leu31,Pro34]-Neuropeptide Y(human,rat) [Leu31,Pro34]-Neuropeptide Y (human, rat)
High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.
TP1338 Neuropeptide Y (29-64), amide, human TFA
Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to prot...
T23094 NTNCB hydrochloride Others , Neuropeptide Y Receptor
NTNCB hydrochloride is an antagonist of neuropeptide Y (NPY) Y5 receptor.
TQ0286 MK-0557 Neuropeptide Y Receptor
MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).
T75734 Neuropeptide Y, porcine
Neuropeptide Y (porcine), a peptide found in the porcine brain, effectively inhibits secretin-stimulated pancreatic secretion [1].
T8963 CYM2503 Neuropeptide Y Receptor
CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor that potentiates galanin-induced IP1 production in vitro. It has no affinity for the orthosteric galanin binding site of the receptor (as measured by ...
T75735 Neuropeptide Y, porcine TFA
Neuropeptide Y, porcine TFA, a peptide found in the pig's brain, effectively inhibits secretin-stimulated pancreatic secretion [1].
T10539 BIBO3304 TFA Neuropeptide Y Receptor
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).
T17222 Velneperit S2367 Neuropeptide Y Receptor
Velneperit (S2367) is potent and selective neuropeptide Y (NPY) Y5 receptor under evaluating for treatment of obesity.
T75730 [D-Arg25]-Neuropeptide Y (human)
[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY), a Y1 receptor selective agonist, plays a role in Alzheimer's disease (AD) and safeguards rat cortical neurons from β-Amyloid toxicity [1].
T76358 Neuropeptide Y (1-24) (human)
Neuropeptide Y (1-24) (human) is a neuropeptide that inhibits the electrically stimulated twitch response in rat vas deferens and activates neurons in the rat CA3 region of the dorsal hippocampus in vivo following N-meth...
T76356 Neuropeptide Y (2-36) (porcine)
Neuropeptide Y (2-36) (porcine) is a pig-sourced peptide closely resembling its rat and human counterparts with 97.14% homology. It acts as an agonist for rat neuropeptide receptors Y5, Y2, and Y1, demonstrating EC50 val...
T83677 Neuropeptide Y (porcine, bovine) TFA NPY (porcine, bovine)
Neuropeptide Y (NPY), a neuropeptide, plays roles in regulating appetite, vasoconstriction, cardiac contractility, and intestinal secretion, acting as an agonist for NPY receptors Y1, Y2, and Y5. Expressed ubiquitously, ...
T5587 CGP71683 hydrochloride CGP71683A Neuropeptide Y Receptor
CGP71683 hydrochloride (CGP71683A) is a competitive neuropeptide Y5 receptor antagonist (Ki: 1.3 nM) and shows no obvious activity at Y1 receptor (Ki >4000 nM) and Y2 receptor (Ki: 200 nM) in cell membranes.
TP1380 Galanin (1-16), mouse, porcine, rat Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.
T1997 JNJ-31020028 JNJ 31020028 Neuropeptide Y Receptor
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.
T5455 HT-2157 SNAP37889,SNAP-37889 Neuropeptide Y Receptor
HT-2157 (SNAP-37889) is a selective, high-affinity competitive antagonist of the galanin-3 receptor (Gal3), demonstrating effective inhibition of this target.
T74350 Neuropeptide Y Y1 receptor antagonist 1
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, serves as a powerful antagonist against the neuropeptide Y Y1 receptor (Y1R), exhibiting a Kᵢ value of 0.19 nM [1]. It should be stored in condi...
T76355 Neuropeptide Y (3-36) (porcine)
Neuropeptide Y (3-36) (porcine) acts as an agonist for the Y2 subtype of the neuropeptide Y (NPY) receptor, effectively stimulating feeding behavior in rats. This compound exhibits high selectivity for the Y2 receptor co...
T76357 Neuropeptide Y (18-36) (porcine)
Neuropeptide Y (18-36) (porcine) acts as a competitive antagonist of the neuropeptide Y (NPY) cardiac receptor, effectively blocking the attachment of I-NPY to cardiac ventricular membranes. Its action is concentration-d...
T75911 [D-Trp34]-Neuropeptide Y TFA
[D-Trp34]-Neuropeptide Y TFA acts as a potent and selective agonist for the neuropeptide Y (NPY) Y5 receptor, demonstrating significantly lower potency at the NPY Y1, Y2, Y4, and Y6 receptors. It has been observed to sig...
T75912 [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA
[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA acts as a specific agonist for the neuropeptide Y Y1 receptor, while also activating receptors Y4 and Y5. This compound is known to elevate blood pressure in anesthetized rats ...
T80143 Galanin (1-13)-Neuropeptide Y (25-36) amide Neuropeptide Y Receptor
Galanin (1-13)-Neuropeptide Y (25-36) amide exhibits high-affinity binding to galanin receptors, similar to that of galanin itself [1].
TP1059 Peptide YY (PYY) (3-36), human Peptide YY (3-36) Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) is a gut hormone peptide. Peptide YY (PYY) (3-36), human acts as a Y2 receptor agonist to reduce appetite.
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T12895 SHA 68 Neuropeptide Y Receptor
SHA 68 is a potent and selective non-peptide antagonist of neuropeptide S receptor (NPSR)(NPSR Asn107 and NPSR Ile107 with IC50s of 22.0 and 23.8 nM, respectively).
T23087 NPY 5RA972 Neuropeptide Y Receptor
neuropeptide Y Y5 receptor antagonist
T12155 Y1 receptor antagonist 1 H 409-22 isomer Neuropeptide Y Receptor
Y1 receptor antagonist 1 (H 409-22 isomer) is the active isomer of H-409/22, a neuropeptide Y (NPY) Y1 receptor antagonist that dose-dependently antagonizes the vascular response to exogenous and endogenous NPY in pigs. ...
T21611L BWX 46 Acetate BWX 46 Acetate(172997-92-1 Free base) Neuropeptide Y Receptor
BWX 46 Acetate is a potent, highly selective neuropeptide Y (NPY) receptor agonist with IC50 of 0.5 nM.
T71321 (S)-VU0637120 Others
(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.
T77783 WAY-639889 Neuropeptide Y Receptor
WAY-639889 is a small molecule compound with selective and potent inhibitory effects on neuropeptide Y-5 receptors.
T23349 SF 11 Others
SF 11 is a potent and brain penetrant neuropeptide Y Y2 receptor antagonist with IC50 of 199 nM. Antidepressant-like activity
TP1137L Pancreatic Polypeptide (human) acetate Neuropeptide Y Receptor
Pancreatic Polypeptide (human) acetate is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
T71749 SF-22 Neuropeptide Y Receptor
SF-22 is a neuropeptide Y receptor (Y2R) antagonist that crosses the blood-brain barrier and has potential anti-inflammatory activity for the study of diseases associated with neurological disorders.
TP1858L Phe-Met-Arg-Phe, amide acetate Phe-Met-Arg-Phe, amide acetate（64190-70-1 freebase) Potassium Channel
Phe-Met-Arg-Phe, amide acetate dose dependently (ED50=23 nM) activates a K+ current in the peptidergic caudodorsal neurons. This peptide appears to localize with neuropeptide Y in some regions of the brain.
T15679 L 152804 Neuropeptide Y Receptor
L 152804 is a specific antagonist of the neuropeptide Y Y5 receptor and modulates food intake and energy expenditure thus causing weight loss in diet-induced obese mice.

Compounds

Neuropeptide Y (29-64), amide, human acetate
TP1140L
Synonym:
Target: Neuropeptide Y Receptor
[Leu31,Pro34]-Neuropeptide Y (porcine)
TP2206
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y (scrambled) Acetate
TP2194L
Synonym: Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate
Target: Others
[D-Trp34]-Neuropeptide Y Acetate
TP1984L
Synonym: [D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
Target: Neuropeptide Y Receptor
Neuropeptide Y (human) (TFA)
T36446
Synonym:
Target:
Neuropeptide Y 13-36 (porcine)
T36447
Synonym:
Target:
Neuropeptide Y (3-36) (human, rat)
T36445
Synonym:
Target:
Neuropeptide Y (human)
TP1140
Synonym: Human neuropeptide Y (29-64),Neuropeptide Y (29-64), amide, human
Target:
Neuropeptide Y (scrambled)
TP2194
Synonym:
Target: Others
[D-Trp34]-Neuropeptide Y
TP1984
Synonym:
Target:
Neuropeptide Y(29-64)
TP1818
Synonym:
Target:
Neuropeptide Y (22-36)
TP1681
Synonym:
Target:
Neuropeptide Y (3-36) (human, rat) (trifluoroacetate salt)
T35599
Synonym:
Target:
Neuropeptide Y (13-36), amide, human
TP1081
Synonym: Neuropeptide Y (13-36), human
Target:
[Leu31,Pro34]-Neuropeptide Y(human,rat)
TP1985
Synonym: [Leu31,Pro34]-Neuropeptide Y (human, rat)
Target:
Neuropeptide Y (29-64), amide, human TFA
TP1338
Synonym:
Target:
NTNCB hydrochloride
T23094
Synonym:
Target: Others, Neuropeptide Y Receptor
MK-0557
TQ0286
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y, porcine
T75734
Synonym:
Target:
CYM2503
T8963
Synonym:
Target: Neuropeptide Y Receptor
Neuropeptide Y, porcine TFA
T75735
Synonym:
Target:
BIBO3304 TFA
T10539
Synonym:
Target: Neuropeptide Y Receptor
Velneperit
T17222
Synonym: S2367
Target: Neuropeptide Y Receptor
[D-Arg25]-Neuropeptide Y (human)
T75730
Synonym:
Target:
Neuropeptide Y (1-24) (human)
T76358
Synonym:
Target:
Neuropeptide Y (2-36) (porcine)
T76356
Synonym:
Target:
Neuropeptide Y (porcine, bovine) TFA
T83677
Synonym: NPY (porcine, bovine)
Target:
CGP71683 hydrochloride
T5587
Synonym: CGP71683A
Target: Neuropeptide Y Receptor
Galanin (1-16), mouse, porcine, rat
TP1380
Synonym:
Target: Neuropeptide Y Receptor
JNJ-31020028
T1997
Synonym: JNJ 31020028
Target: Neuropeptide Y Receptor
HT-2157
T5455
Synonym: SNAP37889,SNAP-37889
Target: Neuropeptide Y Receptor
Neuropeptide Y Y1 receptor antagonist 1
T74350
Synonym:
Target:
Neuropeptide Y (3-36) (porcine)
T76355
Synonym:
Target:
Neuropeptide Y (18-36) (porcine)
T76357
Synonym:
Target:
[D-Trp34]-Neuropeptide Y TFA
T75911
Synonym:
Target:
[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA
T75912
Synonym:
Target:
Galanin (1-13)-Neuropeptide Y (25-36) amide
T80143
Synonym:
Target: Neuropeptide Y Receptor
Peptide YY (PYY) (3-36), human
TP1059
Synonym: Peptide YY (3-36)
Target: Neuropeptide Y Receptor
GALNON
T8456
Synonym:
Target: Neuropeptide Y Receptor
SHA 68
T12895
Synonym:
Target: Neuropeptide Y Receptor
NPY 5RA972
T23087
Synonym:
Target: Neuropeptide Y Receptor
Y1 receptor antagonist 1
T12155
Synonym: H 409-22 isomer
Target: Neuropeptide Y Receptor
BWX 46 Acetate
T21611L
Synonym: BWX 46 Acetate(172997-92-1 Free base)
Target: Neuropeptide Y Receptor
(S)-VU0637120
T71321
Synonym:
Target: Others
WAY-639889
T77783
Synonym:
Target: Neuropeptide Y Receptor
SF 11
T23349
Synonym:
Target: Others
Pancreatic Polypeptide (human) acetate
TP1137L
Synonym:
Target: Neuropeptide Y Receptor
SF-22
T71749
Synonym:
Target: Neuropeptide Y Receptor
Phe-Met-Arg-Phe, amide acetate
TP1858L
Synonym: Phe-Met-Arg-Phe, amide acetate（64190-70-1 freebase)
Target: Potassium Channel
L 152804
T15679
Synonym:
Target: Neuropeptide Y Receptor
1 2

Recombinant Proteins

Species：
Human (3)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (2)
Tag：
N-10xHis (2)
C-6xHis (1)
N-hFc (1)
Cat No. Product Name Species Expression System
TMPY-00286 Neuropeptide Y Protein, Human, Recombinant (hFc) Human HEK293 Cells
NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00007 NPY Protein, Human, Recombinant (His) Human HEK293 Cells
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY ...
TMPH-02809 NPY2R Protein, Mouse, Recombinant (His) Mouse E. coli
Receptor for neuropeptide Y and peptide YY. NPY2R Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 11.0 kDa and the accession number is P972...
TMPH-01767 NPY2R Protein, Human, Recombinant (His) Human E. coli
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY a...
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