Home Tools
Log in
Cart

Search Result

Search Results for " ntd "

12

Compounds

Cat No. Product Name Synonyms Targets
T78811 PROTAC AR-NTD degrader 1 Androgen Receptor
PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal domain (AR-NTD) of the Androgen Receptor variant AR-V7. By antago...
T6829 EPI-001 EPI001,EPI 001 Apoptosis , Androgen Receptor , PPAR
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ~6 μM and a selective PPAR-gamma modulator.
T28502 Ralaniten EPI-002 Androgen Receptor
Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites...
T35841 5-Benzyloxygramine Dopamine Receptor , 5-HT Receptor
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...
T20000 I-XW-053 HIV Protease
I-XW-053 is a capsid targeted HIV-1 replication inhibitor.
T36375 Ralaniten triacetate
Ralaniten triacetate (EPI-506) is a novel pro-drug of Ralaniten, functioning as an orally active inhibitor of the androgen receptor (AR) N-terminal domain (NTD). Its remarkable first-in-class status signifies its unique ...
T71527 NSC145366
NSC145366 is an inhibitor of Hsp90 activities which targets the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. NSC145366 increases Hsp90 oligomerization resulting in alloster...
T75171 BacPROTAC-1
BacPROTAC-1, a potent mSA BacPROTAC degrader, exhibits high affinity for both mSA and the N-terminal domain (NTD) of ClpC, with dissociation constants (K D) of 3.9 μM and 2.8 μM, respectively [1].
T75168 Homo-BacPROTAC7
Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
T78810 BWA-522 Androgen Receptor
BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL) and the AR-V7 splice variant. It specifically antagonizes the...
T75167 Homo-BacPROTAC6
Homo-BacPROTAC6, a ClpC1 NTD BacPROTAC degrader, effectively targets ClpC2, while Homo-BacPROTAC7 has been shown to efficiently kill M. tuberculosis [1].
T83582 (±)-Pantothenic acid (±)-Vitamin B5,(±)-Pantothenate
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is essential for coenzyme A (CoA) biosynthesis in mammalian cells and exhibits protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD...
TargetMol