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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23316 | SB 218795 | Neurokinin receptor | |
SB 218795 is an effective and selective antagonist of NK3 with a Ki 13 nM for hNK3 which is about 90-fold and 7000-fold selectivity over hNK2 and hNK1. | |||
T34717 | Stevastelin B3 | NK374186B3,NK 374186B3,Antibiotic NK 374186B3,NK-374186B3 | |
Stevastelin B3 is a depsipeptide isolated from Penicillium. | |||
T33693 | NK 1971 | NK 266 orotate,2-(2-(3-Heptyl-4-methyl-2-thiazolin-2-ylidene)methine)-3-heptyl-4-methylthiazolium orotate | |
NK 1971 is a bioactive chemical. | |||
TP1086 | Men 10376 TFA(135306-85-3,free) | Men 10376 TFA,Neurokinin-2 receptor antagonist TFA | Neurokinin receptor |
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 M for the nk-2 receptor in the small intestine of rats. | |||
T16849 | SB-222200 | Neurokinin receptor | |
SB-222200 is a selective, reversible, and competitive antagonist of the human NK-3 receptor(Ki=4.4 nM). | |||
T38144 | Elinzanetant | Neurokinin receptor | |
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion. | |||
T8235 | L-732138 | Neurokinin receptor | |
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM) | |||
T2539 | Fingolimod hydrochloride | Fingolimod (FTY720) HCl,FTY720 | TRP/TRPV Channel , S1P Receptor , PAK , LPL Receptor |
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells). | |||
T7549 | Talnetant | SB 223412 | Neurokinin receptor |
Talnetant (SB 223412) is a selective, competitive, brain-penetrant NK3 receptor antagonist with the ability to modulate mesolimbic and mesocortical dopaminergic neurotransmission | |||
T28706 | SCH 206272 | SCH206272,SCH-206272 | |
SCH 206272 is a potent, orally active antagonist of tachykinin NK(1), NK(2), and NK(3) receptor. | |||
T76405 | [D-Trp2,7,9] Substance P | ||
[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist that exhibits inhibitory affinities (K_i values) of 1 μM for NK-1, 1.3 μM for NK-2, and approximately 9 μM for NK-3 receptors [1]. | |||
T76431 | GR 83074 | ||
GR 83074 is a potent and selective antagonist of the NK-2 (Neurokinin Receptor), demonstrating a selectivity factor of 340-fold over NK-1, with a pK B value of 8.23. It does not act as an antagonist for NK-3, affirming i... | |||
T32007 | GSK256471 | GSK 256471,GSK-256471 | |
GSK256471 is a potent selective NK(3) antagonist that shows a high affinity for recombinant human (PK (I) value 8.9) and native guinea pig (PK (I) value 8.4) tachykinin NK(3) receptors. In vitro functional assessment sho... | |||
T75880 | GR 94800 TFA | ||
GR 94800 TFA is a potent, selective antagonist of the NK 2 receptor peptide, demonstrating pK B values of 9.6 for NK 2, 6.4 for NK 1, and 6.0 for NK 3 receptors, respectively [1] [2]. | |||
T80918 | Tuparstobart | Incagn-02385 | |
Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic ... | |||
T76519 | HCV Peptide (35-44) | ||
HCV Peptide (35-44), a core protein of Hepatitis C Virus located at positions 35 to 44, functions as an HLA-A2-restricted CTL epitope and inhibits NK cell activity through two distinct mechanisms: directly through the KI... | |||
T76436 | [MePhe7]-Neurokinin B | ||
[MePhe7]-Neurokinin B is a neurokinin NK-3 receptor (NK3R) agonist, exhibiting a potent agonistic activity with an IC50 value of 3 nM. It acts as a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) s... | |||
T36053 | D-Lysine lactam | ||
D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists. 1.Kumar,... | |||
T77096 | Nemvaleukin alfa | ||
Nemvaleukin alfa (ALKS 4230) is an IL-2 fusion protein that selectively targets intermediate-affinity IL-2R, serving as an activator of NK and effector T cells. This compound is utilized in cancer research [1] [2] [3]. | |||
T74915 | ODN D-SL03 | ||
ODN D-SL03, a class C CpG oligonucleotide, effectively stimulates peripheral blood mononuclear cells (PBMCs) to produce high levels of IFN-α. It activates human B cells, NK cells, and mononuclear cells, elevating the exp... |