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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7519 | RS-127445 hydrochloride | RS 127445,MT 500 | 5-HT Receptor |
RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5). | |||
T9104 | TJ191 | Apoptosis | |
TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. | |||
T68766 | Dp2mT | ||
Dp2mT is an iron chelator which inhibits HIV-1 transcription. | |||
T68484 | 2-MT-63 | ||
2-MT 63 is a novel TIE-2 kinase inhibitor that demonstrates unique and improved kinase selectivity compared to other inhibitors known to interact with TIE-2. 2-MT 63 has a good kinase selectivity profile in enzyme assays... | |||
T61570 | Mt KARI-IN-2 | ||
Mt KARI-IN-2 (compound 5b) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 2.02 μM. This compound also exhibits inhibitory activity against Mtb H37... | |||
T17319 | 1,2-Bis(2-iodoethoxy)ethane | Others , PROTAC Linker | |
1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 and SJF620. MT-802 and SJF620 are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, res... | |||
T4S1521 | 1,4-Dicaffeoylquinic acid | HIV Protease | |
1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration... | |||
T29044 | UCM 765 | UCM-765,UCM765 | |
UCM 765 is a partial agonist of melatonin MT(2) receptor. | |||
T29393 | 3'-Deoxy-4-thiothymidine | Thymidine, 3'-deoxy-4-thio-,Ddthds | |
3'-Deoxy-4-thiothymidine can moderately active in protecting HIV-induced cytopathogenicity of MT-2 and CEM cells. | |||
T7208 | AMD 3465 hexahydrobromide | GENZ-644494 (hexahydrobromide) | HIV Protease , CXCR |
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity. | |||
T10141 | 4'-Ethynyl-2'-deoxyadenosine | Others | |
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a nucleoside reverse transcriptase (RT) inhibitor. It is potent against drug-resistant HIV variants (EC50: 98 nM in MT-4 cells for anti-HIV-1 activity). | |||
T15776 | Loviride | R 89439 | Others |
Loviride is a non-nucleoside reverse transcriptase inhibitor (IC50: 0.3 µM). Loviride inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. It is used for reverse transcriptase from HIV-1. | |||
T72162 | HIV-1 integrase inhibitor 10 | ||
HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus's viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilize... | |||
T37455 | C18 D-threo Ceramide (d18:1/18:0) | C18 D-threo Ceramide (d18:1/18:0) | |
C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koola... | |||
T37749 | Benanomicin A | ||
Benanomicin A is a microbial metabolite that has been found inActinomycetesand has antifungal, fungicidal, and antiviral activities.1,2It is active against a variety of mammalian and plant pathogenic fungi, includingC. a... | |||
T37750 | Benanomicin B (formate) | ||
Benanomicin B is a microbial metabolite that has been found inActinomycetesand has antifungal, fungicidal, and antiviral activities.1,2It is active against a variety of mammalian and plant pathogenic fungi, includingC. a... | |||
T83707 | F9170 TFA | ||
F9170, an antiviral peptide derived from the HIV-1 envelope glycoprotein (amino acids 789-803), targets the LLP1 domain in the virus's envelope protein cytoplasmic tail. This interaction inhibits HIV-1 IIIB infection in ... | |||
T36659 | Boromycin | ||
Boromycin is a boron-containing macrolide antibiotic that has been found in Streptomyces. Boromycin inhibits growth of B. subtilis (MIC = 0.05 μg/ml) and induces efflux of potassium ions from B. subtilis without affectin... | |||
T74664 | KTX-582 | ||
KTX-582 is a potent IRAK4 degrader, exhibiting DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It efficiently induces apoptosis in MYD88 MT DLBCL and has demonstrated effectiveness in inducing in vivo tumor regression... | |||
T62305 | MtTMPK-IN-2 | ||
MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory conce... |