ml-9 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T16104	ML-9		Myosin , Akt
	ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction ...		Myosin , Akt
T16103	ML-9 Free Base		Others
	ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal ...		Others
T4601	9-Methoxycanthin-6-one		Others
	9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg/mL.		Others
T28449	Pradefovir	ICN-2001-3,MB-6866,ICN-20013,MB-06866,Remofovir	HBV
	Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converte...		HBV
T36914	2-Hydroxyanthraquinone		Others
	2-Hydroxyanthraquinone is an anthraquinone that has been found inSpermacoce latifoliaand has antibacterial and estrogenic activities.1,2It is active againstB. subtilisandB. cereus(MICs = 1.9 and 62.5 μg/ml, respectively)...		Others
T74769	Antituberculosis agent-9
	Antituberculosis agent-9 (Compound 5a), an orally administered compound, demonstrates potent antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 0.5 μg/mL against H37Ra [1].
T79974	HIV-IN-8
	HIV-IN-8 (Compound 9) acts as an HIV inhibitor, suppressing HIV replication with an effective concentration (EC50) of 13 μg/mL [1].
T79765	SDH-IN-9
	SDH-IN-9 (compound Ip) serves as a potent Succinate Dehydrogenase inhibitor and exhibits fungicidal properties, effectively targeting Fusarium graminearum Schw at an EC50 value of 0.93 μg/mL [1].
T78866	DNA Gyrase-IN-9		DNA/RNA Synthesis
	DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase. It exhibits a minimum inhibitory concentration (MIC) of 0.5-2 µg/mL for Gram-positive bacteria inhibition and a minimum bactericidal ...		DNA/RNA Synthesis
T82194	HIV-IN-9
	HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT. Additionally, it inhibits the cytochrome P450 isoenzymes CYP3A4, CYP1A2, CYP2C1, and CYP2D6 [1]...
T62754	Anticancer agent 34
	Anticancer agent 34 (compound 9) is a sulfonylurea derivative and a potent anti-microbial and anti-cancer agent. anticancer agent 34 showed inhibition of microbial growth of Mycobacterium, Escherichia coli and Candida al...
T74954	Antimicrobial agent-9
	Antimicrobial Agent-9 (Compound 16) exhibits antimicrobial properties with a minimum inhibitory concentration (MIC) range of 4-8 μg/mL against both gram-positive and gram-negative bacteria, and also demonstrates anti-inf...
T83558	(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone
	(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a palmitate derivative, is extracted from the root of Salvia miltiorrhiza. Compound 3 ...
T80332	Maximin H1
	Maximin H1, an antimicrobial peptide sourced from the skin secretions of the Chinese red belly toad (Bombina maxima), exhibits efficacy against several pathogens, including Escherichia coli (ATCC25922), Staphylococcus au...
T41179	CL 82198 hydrochloride
	CL 82198 hydrochloride is a selective inhibitor of MMP-13 (89% inhibition at 10μg/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibitsin vitroinvasion by the human pituitary adenoma cell line HP75. Rescues pac...
T78599	CK2-IN-9
	CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter activity with an IC50 of 75 nM. In rats, it demonstrates low e...
T78883	DprE1-IN-9
	DprE1-IN-9 (compound B18) is an efficient reversible inhibitor of DprE1, interacting with the enzyme's receptor cavity. It exhibits potent antimycobacterial properties, demonstrating activity against both non-pathogenic ...
TN3325	9-O-Feruloyl-5,5'-dimethoxylariciresinol		IL Receptor , TNF
	(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, ...		IL Receptor , TNF
T36844	Inostamycin A
	Inostamycin A is a bacterial metabolite that has been found inStreptomycesand has anticancer activity.1It is an inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase (IC50= 0.02 μg/ml in A431 cell membranes)...
T35423	7-oxo Staurosporine
	7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respe...