Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | ML-9 (free base) suppresses MLCK, PKA, and PKC activity (Ki: 4, 32, and 54 μM, respectively). ML-9 (free base) is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction molecule 1 (STIM1) activity. ML-9 (free base) causes autophagy by stimulating autophagosome formation and inhibiting their degradation. |
In vitro | ML9 (free base) (50?μM; 1-4?hours) obviously enhances cleaved caspase-3 levels, decreased STIM1 protein levels by about 42%. ML9 (free base) (0-100?μM; 0-24?hours) has no reduction in cardiomyocyte viability, 50-100?μM obviously causes cell death [2]. |
Molecular Weight | 324.83 |
Formula | C15H17ClN2O2S |
CAS No. | 110448-31-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ML-9 Free Base 110448-31-2 Others ML 9 ML9 Free Base ML 9 Free Base ML-9 ML9 inhibitor inhibit