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Search Results for " mi-1 "

13

Compounds

Cat No. Product Name Synonyms Targets
T61735 MI-1 Others
MI-1 inhibits Menin-MLL interaction with an IC 50 of 1.9 μM [1].
T2350 MALT1 inhibitor MI-2 MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor) MALT
MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.
T68398 MI-223 Others
MI-223 is an inhibitor of Mcl-1-stimulated homologous recombination (HR) DNA repair, which leads to sensitization of cancer cells to hydroxyurea- or olaparib-induced DNA replication stress.
T83043 Anti-MI/R injury agent 1 Others
Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R) injury. It improves cell viability in cardiomyocytes subjec...
T6585 SAR405838 MI773,MI 773,MI-77301,MI-773 Mdm2 , E1/E2/E3 Enzyme
MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
T33380 MI-389 PROTACs
MI-389 is a protein degrader, targeting the translation termination factor G1 to S phase transition 1 (GSPT1).
T21898 MI-192 Others
MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC 50 s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. MI-192 has pot...
T74247 TPE-MI
Tetraphenylethene maleimide (TPE-MI) serves as a thiol probe to assess unfolded protein levels and proteostasis within cells. It is particularly effective in identifying proteostasis imbalances in both induced pluripoten...
T77166 Rovelizumab
Rovelizumab, a humanized monoclonal leukointegrin antibody, targets CD11/CD18 cell adhesion proteins. It has potential applications in the research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI...
T73895 MI-1061 TFA Others
MI-1061 TFA, a potent and orally bioavailable MDM2 inhibitor (MDM2-p53 interaction), demonstrates significant chemical stability with an IC 50 of 4.4 nM and a K i of 0.16 nM. It effectively activates p53 and induces apop...
T78887 ROS-IN-2 Reactive Oxygen Species
ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has ...
T73661 Delcasertib hydrochloride
Delcasertib (KAI-9803) hydrochloride, a potent and selective δ-protein kinase C (δPKC) inhibitor, shows promise in reducing ischemia and reperfusion injury in animal models of acute myocardial infarction (MI) [1] [2].
T37963 Methylchloroisothiazolinone/Methylisothiazolinone Mixture Others
Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002,...
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