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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4646 | TA-02 | p38 MAPK , Autophagy | |
TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2. | |||
T2416 | BIX02189 | ERK , MEK , TGF-beta/Smad | |
BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM. | |||
T1744 | BIX02188 | Apoptosis , MEK | |
BIX02188 is a selective and potent MEK5 inhibitor that inhibits MEK5-induced apoptosis in cells expressing the oncogenic mutant FLT3-ITD. | |||
T6324 | (E/Z)-BIX02188 | 334949-59-6 | ERK , MEK , TGF-beta/Smad |
BIX02188 is a specific MEK5 inhibitor (IC50: 4.3 nM), also inhibits ERK5 catalytic activity (IC50: 810 nM), and does not inhibit closely related kinases MEK1/2, JNK2, and ERK2. | |||
T7610 | GW284543 | UNC10225170 | MEK |
GW284543 (UNC10225170) is a selective inhibitor of MEK5 . | |||
T21295 | BIX02189 | BIX 02189 | ERK , MEK |
BIX02189 is a potent and selective inhibitor of MEK5 and ERK5(IC50 : 1.5 nM and 59 nM). | |||
T7742 | GW 284543 hydrochloride | MEK | |
GW 284543 hydrochloride is a selective inhibitor of MEK5 . | |||
T78154 | CS640 | ||
CS640 is a selective calmodulin-dependent kinase inhibitor, targeting multiple isoforms, namely CaMK1D, CaMK1B, CaMK1A, CaMK1G, PIP5K1C, MEK5, RIPK4, and MLK3, with respective IC50 values of 0.08, 0.03, 0.001, 0.001, 11.... |