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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11940 | Malic enzyme inhibitor ME1 | ME1 | Others |
Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity. | |||
T18613 | MV-1-NH-Me | PROTAC IAP binding moiety 2 | Others |
MV-1-NH-Me, an MV-1-derived IAP ligand, connects to an ABL inhibitor through a linker, resulting in the formation of SNIPER[1]. | |||
T13671 | (S,R,S)-AHPC-Me hydrochloride | VHL ligand 2 hydrochloride,E3 ligase Ligand 1 | Others , Ligand for E3 Ligase |
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cell... | |||
T9016 | AI-10-47 | 1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 | Others |
AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) is a small molecule inhibitor of CBFβ-RUNX binding(IC50 : 3.2 μM). | |||
T18612 | Bestatin-amido-Me | PROTAC IAP binding moiety 1 | Others |
Bestatin-amido-Me, a derivative of Bestatin, acts as an IAP ligand and interacts with ABL inhibitor through a linker to produce SNIPER[1]. | |||
T13671L | (S,R,S)-AHPC-Me dihydrochloride | VHL ligand 2 dihydrochloride,E3 ligase Ligand 1 dihydrochloride,(S,R,S)-AHPC-Me dihydrochloride (1948273-02-6 free base) | Others |
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demon... | |||
T76631 | (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) | ||
E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid receptor (KOR) agonist [1]. | |||
T130490 | 1-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-Me et | ||
1-(3,4-Dihydroxyphenyl)-1-propanol, 3?,4?-Di-Me et is a useful organic compound for research related to life sciences and the catalog number is T130490. | |||
T39910 | Desmorpholinyl Navitoclax-NH-Me | Desmorpholinyl ABT-263-NH-Me,Desmorpholinyl Navitoclax-NH-Me | BCL |
Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2]. | |||
T18363 | Monoethyl pimelate | Others , PROTAC Linker | |
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1]. | |||
T7752 | (S,R,S)-AHPC-Me | VHL ligand 2,E3 ligase Ligand 1A | Ligand for E3 Ligase |
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771. ARV-771 is a... | |||
T3S2259 | Methyl eugenol | 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether | GABA Receptor |
1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its... | |||
T82337 | Ganoderic acid Me | ||
Ganoderic acid Me, a triterpenoid present in Ganoderma lucidum [1], exhibits various biological activities. | |||
T4S0969 | Obtusifolin | Antioxidant , NF-κB | |
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be... | |||
T18847 | THP-PEG4-Pyrrolidine(N-Me)-CH2OH | Others | |
THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1]. | |||
T18506 | NO2-SPP-sulfo-Me | Others | |
NO2-SPP-sulfo-Me is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADC)[1]. | |||
T18670 | (S,R,S)-AHPC-Me-C5-COOH | Others | |
(S,R,S)-AHPC-Me-C5-COOH is a synthetic E3 ligase ligand-linker conjugate consisting of a VHL ligand and a linker. It finds application in PROTAC DT2216[1]. | |||
T80941 | Triptonoterpene Me ether | ||
Triptonoterpene Me ether (compound 5), a rosinane-type diterpenoid, is derived from the traditional Chinese medicinal plant, Tripterygium wilfordii Hook. f [1]. | |||
T16236 | N-Me-N-bis(PEG2-propargyl) | Others | |
N-Me-N-bis(PEG2-propargyl) is a PEG-based linker employed for the synthesis of PROTACs[1]. | |||
T18669 | (S,R,S)-AHPC-Me-C10-NH2 | Others | |
(S,R,S)-AHPC-Me-C10-NH2 is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate that incorporates both a VHL ligand and a linker. This compound, (S,R,S)-AHPC-Me-C10-NH2, finds application in ... |