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Search Results for " mbl "

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T79317	MBL-IN-1
	MBL-IN-1 (compound 41), a β-Lactamase inhibitor, exhibits an IC50 range of 0.10 to 25.85 µM and is utilized in the study of bacterial infections [1].
T60092	CHEMBL1276927	N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide	Antibacterial , Parasite
	CHEMBL1276927 (N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide) shows antibacterial and antiparasitic activities against Chlamydia pneumoniae and Leishmania donovani.		Antibacterial , Parasite
T22175L	ZIP (SCRAMBLED) Acetate	ZIP (SCRAMBLED) Acetate(908012-18-0 Free Base)	Others
	ZIP (SCRAMBLED) Acetate (ZIP (SCRAMBLED) Acetate (908012-18-0 Free Base)) is a scrambled peptide that can be used as a negative control for zeta inhibitory peptide (ZIP).		Others
TP2194L	Neuropeptide Y (scrambled) Acetate	Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate	Others
	Neuropeptide Y (scrambled) Acetate (Pro-Neuropeptide Y (scrambled) Acetate) is a scrambled peptide of Neuropeptide Y that has been implicated in Alzheimer's disease (AD) and may have neuroprotective effects.		Others
TP1686L	JAG-1, scrambled TFA(402941-23-5 free base）		Others
	JAG-1, scrambled TFA is a scrambled sequence of JAG-1(188-204).		Others
T8598	CHEMBL241987	2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE	Adenosine Receptor
	CHEMBL241987 targets the Adenosine receptor A3 (human)		Adenosine Receptor
T60093	CHEMBL1380345	N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)	Antibacterial
	CHEMBL1380345 exhibits antibacterial activity against Staphylococcus aureus, Bacillus cereus, and Escherichia coli with pMIC values of 3.64, 3.56, and 3.70, respectively.		Antibacterial
TP1585	Sgp91 ds-tat Peptide 2, scrambled
	This peptide is a scrambled sequence of NADPH oxidase assembly peptide inhibitor gp91 ds-tat. It is used as a control peptide. It is two amino acid residues shorter at the N-terminus compared to the scrambled gp91 ds-tat...
T68384	SCHEMBL12616233
	SCHEMBL12616233 is a novel inhibitor of SARS-CoV-2 main protease (MPro).
T28749	SEMBL
	SEMBL, a novel inhibitor of DNA binding of NF-kappaB component p65 in vitro, inhibits NF-kappaB and cellular invasion in ovarian carcinoma ES-2 cells.
TP1825	LL-37 scrambled peptide
	LL-37 scrambled peptide is a scrambled version of cathelicidin anti-microbial peptide LL-37.
TP2194	Neuropeptide Y (scrambled)		Others
	Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiologi...		Others
T71902	CHEMBL94431
	CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase.
TP1686	JAG-1, scrambled
	This peptide is a scrambled sequence of JAG-1(188-204).
T38743	Scrambled TRAP Fragment
	Scrambled TRAP Fragment is a variant of the TRAP Fragment compound, characterized by its random amino acid sequence. It is typically employed as a negative control due to its similarity in composition to the active fragm...
T81450	PKCε Inhibitor Scramble Peptide
	PKCε Inhibitor Scramble Peptide consists of the same amino acid sequence as the PKCε inhibitor peptide, but in a randomized order.
T75968	LL-37 scrambled peptide acetate
	LL-37 scrambled peptide acetate is a scrambled peptide of cathepsin antimicrobial peptide LL-37, which is often used as a negative control for LL-37 peptide in experiments.
T27386	FR-295389	FR-295389 Free Base,FR295389
	FR-295389 is a cephalosporin. FR-295389 shows effective antibacterial activity against metallo-beta-lactamase (MBL)-producers in vitro.
T74849	EBL-3183
	EBL-3183, an indole-2-carboxylate, serves as a potent, reversible, non-covalent, and competitive inhibitor of metallo-β-lactamase (MBL), specifically targeting NDM-1 with a pIC50 of 7.7 [1].
T60370	Metallo-β-lactamase-IN-2
	Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1].
T60694	Metallo-β-lactamase-IN-4
	Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1].
T72261	Metallo-β-lactamase-IN-9
	Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1].
T60239	Metallo-β-lactamase-IN-6
	Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac...
T60282	Metallo-β-lactamase-IN-3
	Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ...

Compounds

Synonym: N-[3-(1H-benzimidazol-2-yl)phenyl]-3-methylbenzamide,N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-3-methylbenzamide

Target: Antibacterial, Parasite

ZIP (SCRAMBLED) Acetate

T22175L

Synonym: ZIP (SCRAMBLED) Acetate(908012-18-0 Free Base)

Target: Others

Neuropeptide Y (scrambled) Acetate

TP2194L

Synonym: Pro-Neuropeptide Y (scrambled) Acetate,NPY (scrambled) Acetate

Target: Others

JAG-1, scrambled TFA(402941-23-5 free base）

Synonym: 2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE

Target: Adenosine Receptor

CHEMBL1380345

T60093

Synonym: N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide)

Target: Antibacterial

sgp91 ds-tat Peptide 2, scrambled

LL-37 scrambled peptide

TP1825

Synonym:

Target:

Neuropeptide Y (scrambled)

Scrambled TRAP Fragment

T38743

Synonym:

Target:

PKCε Inhibitor Scramble Peptide

T81450

Synonym:

Target:

LL-37 scrambled peptide acetate

Synonym: FR-295389 Free Base,FR295389

Metallo-β-lactamase-IN-2

T60370

Synonym:

Target:

Metallo-β-lactamase-IN-4

T60694

Synonym:

Target:

Metallo-β-lactamase-IN-9

T72261

Synonym:

Target:

Metallo-β-lactamase-IN-6

T60239

Synonym:

Target:

Metallo-β-lactamase-IN-3

T60282

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03565	Mannan Binding Lectin/MBL2 Protein, Human, Recombinant	Human	CHO Cells
	Mannan Binding Lectin/MBL2 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 24 kDa and the accession number is P11226.
TMPY-00429	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P41317.
TMPY-04322	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P41317.
TMPY-00993	MBL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	MBL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P39039-1.
TMPJ-00133	MBL2 Protein, Mouse, Recombinant	Mouse	HEK293 Cells
	Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to oc...
TMPJ-00136	MBL2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural f...
TMPK-01202	CD93/C1qR1 Protein, Human, Recombinant (His&Avi), Biotinylated	Human	HEK293 Cells
	CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperrespons...
TMPH-03327	MBL2 Protein, Rat, Recombinant (His)	Rat	E. coli
	Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as...
TMPY-02452	CMBL Protein, Human, Recombinant (His)	Human	E. coli
	Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase, and carboxymethylene butenolide hydrolase, is a hydrolase spe...
TMPY-03473	MBL1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P19999.
TMPK-00705	MASP2 Protein, Human, Recombinant (His)	Human	E. coli
	The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As...
TMPJ-00980	Complement Factor MASP3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of micro...
TMPY-02596	GLT25D2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide ...
TMPJ-01064	Serpin G1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement sy...