latanoprost — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2528	Latanoprost	Xalatan,PHXA41	GPR , Prostaglandin Receptor , RAR/RXR
	Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.		GPR , Prostaglandin Receptor , RAR/RXR
T15718	Latanoprost acid		GPR
	Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about low...		GPR
T37932	15-keto Latanoprost
	Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto latanoprost. 15...
T37625	Latanoprost amide
	Latanoprost amide is a derivative of latanoprost . N/A
T37214	5-trans Latanoprost (free acid)
	Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endog...
T37931	15(S)-Latanoprost
	15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6...
T37213	5-trans Latanoprost
	Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost is an isomer of latanoprost wherein the double bond between carbons 5 and 6 has been chan...
T37626	Latanoprost dimethyl amide
	Latanoprost dimethyl amide is a derivative of latanoprost and an isomer of latanoprost ethyl amide . N/A
T37627	Latanoprost ethyl amide
	Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-e...
T11821	Latanoprost lactone diol		Others
	Latanoprost lactone diol is an important intermediate compound in the synthesis of Latanoprost. Latanoprost, classified as a prostaglandin F2α analogue, functions as an agonist for the FP prostanoid receptor, resulting i...		Others
T37933	15-keto Latanoprost (free acid)
	15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Althou...
T15719	Latanoprostene bunod	LBN,NCX116	Others
	Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o...		Others
T37943	17-phenyl trinor Prostaglandin F2α isopropyl ester	17-phenyl trinor Prostaglandin F2α isopropyl ester
	17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod...
T37948	17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α	17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
	A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relat...
T37947	17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester	17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester
	Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-triflu...
T37777	17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide	17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide
	Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2...
T37939	N-Desethyl Bimatoprost	17-phenyl trinor Prostaglandin F2α amide
	N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. P...
T37724	Lumula
	There are currently four prostaglandin (PG) derivatives which have been approved for human clinical use for the treatment of glaucoma. The names of the PGs and the concentrations of the approved doses are: travoprost (40...
T37934	15-keto-17-phenyl trinor Prostaglandin F2α	15-keto-17-phenyl trinor Prostaglandin F2α
	Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trin...