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Cat No. | Product Name | Synonyms | Targets |
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T77677 | 12R-LOX-IN-2 | Lipoxygenase | |
12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein... | |||
T83457 | 12R-LOX-IN-1 | ||
12R-LOX-IN-1 (Compound 4a), with an IC50 of 28.25 µM, is an inhibitor of 12R-LOX. It suppresses the hyperproliferative condition and the ability to form colonies in Imiquimod-induced psoriatic keratinocytes, as well as r... | |||
T60661 | CP681301 | ||
CP681301 is a potent inhibitor of CDK5 with antiproliferative activity. CP681301 exhibits anti-tumor activity in Drosophila. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in Glioma st... | |||
T79699 | Anti-TNBC agent-2 | Apoptosis | |
Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic. It promotes apoptosis in MDA-MB-231 cells, while also inhibiting their migration and angiogenesis. Moreover, ... |
Cat No. | Product Name | Synonyms | Targets |
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T64353 | 4-tert-Octylphenol | Endogenous Metabolite | |
4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), m... |
Cat No. | Product Name | Species | Expression System |
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TMPJ-01436 | MKI67 Protein, Human, Recombinant (GST) | Human | E. coli |
MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferatio... | |||
TMPY-03105 | Ki67/MKI67 Protein, Human, Recombinant (GST) | Human | E. coli |
MKI67 contains 1 FHA domain and plays a key role in cell proliferation. During interphase, the MKI67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the... | |||
TMPH-01917 | MKI67 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
MKI67 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-01918 | MKI67 Protein, Human, Recombinant (His) | Human | Yeast |
MKI67 Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPK-00868 | Notch 4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The Notch signaling pathway is important for cell-cell communication; it is involved in gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. Notch-4 expression ... |