kd-16 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25487	Haloperidol decanoate	KD 16,KD-136,KD 136,Neoperidole,Haldol	Others
	Haloperidol decanoate (KD 16) is a typical antipsychotic agent utilized as maintenance treatment for schizophrenia and mood disorders formulated as an ester for intramuscular injection.		Others
T6305	SNX2112	SNX-2112,PF 04928473,SNX 2112	HSP
	SNX2112 (PF 04928473) is an orally active Hsp90 inhibitor, with a Kd of 16 nM.		HSP
TP1380	Galanin (1-16), mouse, porcine, rat		Neuropeptide Y Receptor
	Galanin (1-16), mouse, porcine, rat is a hippocampal galanin receptor agonist(Kd = 3 nM) with high biological activity on locus coeruleus neurons.		Neuropeptide Y Receptor
T16334	NMS-P515		Others
	NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.		Others
TP1317	Galanin (1-16), mouse, porcine, rat TFA
	Galanin (1-16), mouse, porcine, rat is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM. Galanin (1-16), mouse, porcine, rat shows high biological activity on locus coeruleus neurons.
T60556	SARS-CoV-2-IN-16
	SARS-CoV-2-IN-16 (Compound 12) is a potent inhibitor of SARS-CoV-2 nucleocapsid protein (NPro) with potent antiviral activity (EC50 = 3.69 μM). SARS-CoV-2-IN-16 binds to NPro with a low Kd value of 7.82 μM, which suggest...
T60251	GID4 Ligand 3
	GID4 Ligand 3 (compound 16) is a binder of GID4 with an Kd value of 110 μM in vitro and an IC 50 value of 148.5 μM. GID4 Ligand 3 can be used in the relevant research of cereblon(CRBN) and Von Hippel-Lindau(VHL) [1].
T61613	SARS-CoV-2-IN-17
	SARS-CoV-2-IN-17 (Compound 16) is a highly effective inhibitor of SARS-CoV-2 nucleocapsid protein (NPro). It demonstrates potent anti-viral activity, with an EC50 value of 2.18 μM. Furthermore, SARS-CoV-2-IN-17 binds to ...
T77148	Pegdinetanib
	Pegdinetanib (BMS-844203; CT-322) is a selective inhibitor targeting VEGFR-2 (VEGFR), exhibiting dissociation constants (Kd) of 11 nM and 250 nM and half-maximal inhibitory concentrations (IC50) of 16 nM and 240 nM for h...
T36292	NSC 12
	NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate ...
T11896	LV-320		Cysteine Protease
	LV-320 is a potent and uncompetitive ATG4B inhibitor with an IC 50 of 24.5 μM and a K d of 16 μM. LV-320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non-toxic and active in vivo. Th...		Cysteine Protease
T36890	A 410099.1
	High affinity XIAP antagonist (Kd = 16 nM for the BIR3 domain of XIAP). Exhibits cytotoxicity in a wide range of cancer cell lines in vitro (EC50 = 13 nM in MDA-MB-231 cells). Also displays antitumor activity in a mouse ...
T10840L	CM-579		DNA Methyltransferase , Histone Methyltransferase
	CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.		DNA Methyltransferase , Histone Methyltransferase
T10840	CM-579 trihydrochloride (1846570-40-8 free base)	CM-579 trihydrochloride	DNA Methyltransferase
	CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.		DNA Methyltransferase