2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6865 | Quisinostat dihydrochloride | Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl | Apoptosis , HDAC , Autophagy |
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; g... | |||
T2243 | Serdemetan | JNJ-26854165 | Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53 |
Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity. |