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Search Results for " jak1-in-8 "

4

Compounds

Cat No. Product Name Synonyms Targets
T35899 JAK1-IN-8 JAK1-IN-8 JAK
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
T2638 Gandotinib LY2784544 VEGFR , FGFR , FLT , JAK
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM). The selectivity is higher 8- and 20-fold than JAK1 and JAK3.
T9764 JAK-IN-14
JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC 50 of <5 μM. JAK-IN-14 is more than 8-fold selective for JAK1 than JAK2 and JAK3 [1].
T78175 JAK-IN-25 JAK
JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. It also demonstrates an IC50 of 28 nM against human whole blood IL-12 (HEB IL-1...
TargetMol