interleukin-19 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9911	Tocilizumab		Interleukin
	Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor		Interleukin
T63315	IRAK4-IN-19
	IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 4.3 nM).IRAK4-IN-19 inhibits LPS-induced IL23 production in THP and DC cells and suppresses the development of arthritis in a...
T36534	SDZ 224-015	SDZ 224015	IL Receptor , Caspase
	SDZ 224-015 is an orally active inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1.SDZ 224-015 exhibits anti-COVID-19 and anti-inflammatory activity, and reduces carrageenan gum-induced paw edema in rats...		IL Receptor , Caspase
T73372	GNE-2256
	GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
T39106	BMSpep-57
	BMSpep-57, a potent macrocyclic peptide inhibitor, competitively disrupts the PD-1/PD-L1 interaction, demonstrating a significant inhibitory concentration (IC50) of 7.68 nM. It exhibits binding affinity towards PD-L1 wit...
T76675	Clazakizumab
	Clazakizumab, a monoclonal antibody, demonstrates high affinity and specificity towards the interleukin-6 (IL-6) cytokine, potentially inhibiting the cytokine response in COVID-19 caused by SARS-CoV-2. It is also under r...

Compounds

Tocilizumab

T9911

Synonym:

Target: Interleukin

Target: IL Receptor, Caspase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00841	IL-13RA2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-13RA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q14627.
TMPY-04874	IL-23 P19/IL23A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7.
TMPY-00493	IL-19 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	The molecular features at the IL19 locus may modestly alter the establishment of HIV-1 infection. Interleukin (IL) 19, IL-20, and IL-24 belong to the IL-10 cytokine family and have been identified to play a role in the r...
TMPK-01229	IL-19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin-19 (IL-19) has been shown to be involved in coronary artery diseases and atherosclerosis, while its expression in myocardial infarction is poorly understood. In this study, the dynamic increase in circulating...
TMPY-05334	IL-13RA2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IL-13RA2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q14627.
TMPY-00842	IL-13RA2 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	IL-13RA2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q14627.
TMPY-04987	IL-23 P19/IL23A Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9NPF7.
TMPK-01169	IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells...
TMPJ-00909	IL-1RA Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and int...