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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27617 | Inz-1 | P450 | |
Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human. Inz-1 reverses Fluconazole or other triazole antifungals’ resistance in the path... | |||
T1887 | Inauhzin | INZ | Sirtuin |
Inauhzin (INZ)(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human Y cells without causing apparently genotoxic stress(IC50=3 uM, in A54... | |||
T15587 | Inz-5 | Others | |
Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance. | |||
T27618 | Inz-4 | ||
Inz-4 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. | |||
T38144 | Elinzanetant | Neurokinin receptor | |
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion. | |||
T25742 | Linzagolix choline | GNRH Receptor | |
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibroids and endometriosis. | |||
T27837 | Linzagolix | GNRH Receptor | |
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharmaceutical and ObsEva for the treatment of uterine fibroids,... | |||
T62304 | Minzasolmin | (R)-NPT200-11,UCB0599,DLX-313 | Others |
Minzasolmin(DLX-313) is an alpha-synuclein misfolding inhibitor for the study of Parkinson's disease. | |||
T0142 | Brinzolamide | AL-4862 | Carbonic Anhydrase |
Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor. | |||
T31240 | Deacetoxyvinzolidine | KAR-2,KAR2,KAR 2 | |
Deacetoxyvinzolidine is a bioactive agent. | |||
T35713 | N-desethyl Brinzolamide (oxalate) | ||
N-desethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1It inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively). 1.Kim, C.-Y., Whittington, D.A., Chang... | |||
T64241 | Brinzolamide hydrochloride | ||
Brinzolamide (AL-4862) hydrochloride is a selective inhibitor (IC50: 3.2 nM) of carbonic anhydrase II. Brinzolamide hydrochloride inhibits ciliary CA-II and reduces atrial fluid secretion, thereby reducing intraocular pr... | |||
T76906 | Anrukinzumab | ||
Anrukinzumab (IMA-638), a humanized anti-IL-13 monoclonal antibody, effectively reduces lung inflammation in cynomolgus monkeys and shows potential in the studies of ulcerative colitis (UC) and asthma [1] [2] [3]. | |||
T37403 | O-desmethyl Brinzolamide (hydrochloride) | ||
O-desmethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1,2It inhibits CAII and CAIV (IC50s = 0.136 and 165 nM, respectively).1 1.Huang, Q., Rui, E.Y., Cobbs, M., et al.Des... | |||
T35761 | Carviolin | ||
Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes... |