icam1 — TargetMol Chemicals

Cat No.	Product Name	Targets
T14676	BMS-688521	Integrin
	BMS-688521 BMS-688521 is an orally active and potent inhibitor of LFA-1/ICAM interaction, a small molecule antagonist of leukocyte function-associated antigen-1 (LFA-1), with potential anti-inflammatory activity.	Integrin
T21781	A-286982	Integrin
	A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.	Integrin
T13147	ICAM-1-IN-1	Integrin
	ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.	Integrin
T2254	A-205804	Integrin
	A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.	Integrin
T12783	RWJ 50271	Integrin
	RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).	Integrin

Compounds

BMS-688521

T14676

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00324	ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is inc...
TMPY-00981	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.2 kDa and the accession number is A0A384MEK5.
TMPY-01142	ICAM-1/CD54 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A0A384MEK5.
TMPK-00872	ICAM-1/CD54 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-...
TMPK-00497	ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-...
TMPY-05393	ICAM-1/CD54 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 76.2 kDa and the accession number is A0A384MEK5.
TMPY-06778	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is NP_000192.2.
TMPY-00825	ICAM-1/CD54 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 77.4 kDa and the accession number is A0A384MEK5.
TMPY-06777	ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 52.77 kDa and the accession number is NP_000192.2.
TMPH-01559	IL-26 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPH-01560	IL-26 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expre...
TMPJ-00432	GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell res...