Shopping Cart

Remove All
Your shopping cart is currently empty

A-205804

Name: A-205804
Brand: TargetMol
SKU: T2254
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2254Cas No. 251992-66-2

A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.

A-205804

🥰Excellent

Purity: 98.52%

Catalog No. T2254Cas No. 251992-66-2

A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.

Pack Size	Price	Availability
2 mg	$37	In Stock
5 mg	$48	In Stock
10 mg	$74	In Stock
25 mg	$163	In Stock
50 mg	$286	In Stock
100 mg	$561	In Stock
500 mg	$1,230	In Stock
1 mL x 10 mM (in DMSO)	$65	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.52%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.
Targets&IC50	ICAM1:25 nM, Eselectin:20 nM
In vivo	In human endothelial cells, A-205804 selectively inhibited ICAM-1 (IC50 = 10 nM) and E-selectin (IC50 = 20 nM).

Chemical Properties

Molecular Weight	300.4
Formula	C₁₅H₁₂N₂OS₂
Cas No.	251992-66-2
Smiles	Cc1ccc(Sc2cncc3sc(cc23)C(N)=O)cc1
Relative Density.	1.40 g/cm3 (Predicted)
Color	Yellow
Appearance	solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 3 mg/mL (9.99 mM), Sonication is recommended.

DMSO: 30 mg/mL (99.87 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3289 mL	16.6445 mL	33.2889 mL	166.4447 mL
5 mM	0.6658 mL	3.3289 mL	6.6578 mL	33.2889 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.3329 mL	1.6644 mL	3.3289 mL	16.6445 mL
20 mM	0.1664 mL	0.8322 mL	1.6644 mL	8.3222 mL
50 mM	0.0666 mL	0.3329 mL	0.6658 mL	3.3289 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc