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Search Results for " h929 "

5

Compounds

Cat No. Product Name Synonyms Targets
T7791 Iberdomide CC-220 Apoptosis , Ligand for E3 Ligase
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
T14918 CDK9-IN-2 Others , CDK
CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.
T7522 GI254023X GI 254023X MMP , Immunology/Inflammation related
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis...
T69766 Gusacitinib HCl
Gusacitinib, also known as ASN-002 and EN-3351, is a potent dual inhibitor of SYK/JAK kinases. ASN002 showed strong antitumor activity in both hematological and solid tumor xenograft models. ASN002 strongly suppressed ...
T28498L Rac-CCT-250863 HCl rac-CCT-250863 HCl(1364269-06-6 Free base) Apoptosis
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combinati...
TargetMol