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Search Results for " grp94 "

16

Compounds

Cat No. Product Name Synonyms Targets
T7261 Grp94 Inhibitor-1 GPR , HSP
Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
T70088 Grp94-IN-2
Grp94-IN-2 is a inhibitor of Grp94.
T70087 EPZ032597 Histone Methyltransferase
EPZ032597 is a novel selective inhibitor of SMYD2 with an IC50 of 16 nM. EPZ032597 has anticancer activity and can be used to prevent and treat pancreatic cancer.
T8958 PU-H54 GPR
PU-H54 is a purine-based inhibitor of Grp94. It is a Grp94-selective resorcinol-based inhibitor isolated through probing of the exclusive binding region of S2 subpocket in Grp94.
T30480 BiP inducer X BIX Apoptosis
BiP inducer X (BIX) is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
T2114 VER-82576 NVP-BEP800 HSP
VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.
T5351L PU-WS13 hydrobromide PU-WS13 hydrobromide (1454619-14-7 Free base) GPR
PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.
T6118 NVP-HSP990 HSP990 Apoptosis , HSP
NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).
T24704 Radamide
Radamide is an inhibitor of Grp94.
T20890 Alvespimycin 17-DMAG,KOS1022,KOS 1022,KOS-1022 HSP
Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.
T27755 KUNG38 KUNG-38,KUNG 38
KUNG38 is a purine-based inhibitor of Grp94.
T24687 PU-H54-iso PU H54-iso,PUH54-iso
PU-H54-iso is a novel Hsp90- and Grp94-selective inhibitor.
T27756 KUNG94 KUNG 94,KUNG-94
KUNG94 is a potent and selective inhibitor of Glucose regulated protein 94 (Grp94) (IC50 = 8 nM), the endoplasmic reticulum resident of the 90 kDa heat shock protein (Hsp90) family.
T79285 TRAP1-IN-1 HSP
TRAP1-IN-1 (compound 35) is a potent, selective TRAP1 inhibitor affecting the mitochondrial variant of Hsp90. It exhibits over 250-fold greater selectivity for TRAP1 compared to Grp94, destabilizes TRAP1 tetramers, and p...
T12726 Retaspimycin Others
Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).
T12726L Retaspimycin Hydrochloride IPI-504 Others
Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).
TargetMol