glutaminase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3964	Glutaminase C-IN-1	Compound 968,Glutaminase Inhibitor Compound 968	Glutaminase
	Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.		Glutaminase
T37385	Glutaminase-IN-3		Glutaminase
	Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.		Glutaminase
T11421	Glutaminase-IN-1	CB839 derivative	transporter
	Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model.		transporter
T78892	Glutaminase C-IN-2		Glutaminase
	Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM. By disrupting glutamine metabolism, this compound modulates cellular metabol...		Glutaminase
T63137	Glutaminase-IN-4
	Glutaminase-IN-4 (compound 2a) is a glutaminase (GLS) inhibitor (IC50: 2.3 μM).
T83914	Glutaminase C Inhibitor 11
	Glutaminase C Inhibitor 11 is a potent inhibitor specifically targeting Glutaminase C (GAC), demonstrating significant inhibition of GAC enzyme activity with an EC50 value of 10.64 nM. It effectively diminishes the viabi...
T6791	BPTES		transporter , Glutaminase
	BPTES(IC50 of 0.16 μM) is an effective and specific GlutamiN/Ase GLS1 (KGA) inhibitor.		transporter , Glutaminase
T3968	GK921		Glutaminase
	GK921 is a transglutaminase 2 (TGase) inhibitor.		Glutaminase
T6797	Telaglenastat	CB 839,CB839,CB-839	transporter , Glutaminase , Autophagy
	Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.		transporter , Glutaminase , Autophagy
T20121	L-Albizziin	NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin	Glutaminase
	L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.		Glutaminase
T8373	6-Diazo-5-oxo-L-nor-Leucine	DON,L-6-Diazo-5-oxonorleucine,Diazooxonorleucine	Influenza Virus , Glutaminase , Antibacterial , Antibiotic
	6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is an antagonist of glutaminases (Ki : 6 μM). It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil.		Influenza Virus , Glutaminase , Antibacterial , Antibiotic
T78362	Transglutaminase	TG
	Transglutaminase (TG) is a thiolase that induces intermolecular cross-linking of proteins, by catalysing the formation of isopeptide bonds between the γ-carboxamide group of glutamine residues and the primary ε-amine gro...
T17206	UPGL00004		Others , Glutaminase
	UPGL00004 is a potent glutaminase C (GAC) inhibitor with an IC50 of 29 nM. Kd of UPGL00004 for GAC was 27 nM. UPGL00004 has a strong inhibitory effect on the proliferation of highly aggressive triple negative breast canc...		Others , Glutaminase
T11412	IPN60090	GLS1-IN-1	Others , transporter
	IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, se...		Others , transporter
T39309	Telaglenastat hydrochloride	CB-839 hydrochloride
	Telaglenastat (CB-839) hydrochloride is a first-in-class, reversible, and orally active inhibitor of glutaminase 1 (GLS1). It selectively inhibits the splice variants of GLS1, specifically KGA (kidney-type glutaminase) a...
T15613	JHU-083		Others
	JHU-083 is a selective glutaminase antagonist. JHU-083 blocks glutaminase activity in brain CD11b+ cells. JHU-083 also experimental cerebral malaria (ECM) resulting in a net decrease of glutamate levels in the animals.		Others
T28961	THDP-17	THDP 17,THDP17
	THDP-17 is a inhibitor of glutaminase. THDP-17 shows a partial uncompetitive inhibition in vitro.
T64259	GLS1 Inhibitor-5
	GLS1 Inhibitor-5 (compound 24y) is a selective, orally active inhibitor of glutaminase 1 (GLS1) (IC50: 68 nM). gLS1 Inhibitor-5 induces apoptosis and exhibits anti-tumour effects.
T37222	GLS1 Inhibitor
	GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM).1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro(GI50= 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growt...
T39544	IPN60090 dihydrochloride	IPN60090 dihydrochloride
	IPN-60090 dihydrochloride is a potent and specific inhibitor of glutaminase 1 (GLS1) with a remarkable inhibition constant (IC50) of 31 nM. It does not exhibit any inhibitory activity against GLS-2. Furthermore, IPN-6009...