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Search Results for " glucokinase "

20

Compounds

Cat No. Product Name Synonyms Targets
T11418 Glucokinase activator 1 Others
Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).
T72284 Glucokinase activator 3
Glucokinase Activator 3, a highly potent and complete activator of Glucokinase (GK), exhibits an AC50 value of 38 nM. This compound holds potential for type 2 diabetes research applications.
TQ0055 AMG-3969 Glucokinase
AMG-3969 is an effective glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor (IC50: 4 nM).
T16479 PF-04937319 Others , Glucokinase
PF-04937319 is an activator of glucokinase (EC50 =154.4  μM). PF-04937319 maintains glucose-lowering efficacy while mitigating the risk of hypoglycemia observed with many other glucokinase activators. PF-04937319 can be ...
T3312 AM-2394 AM2394 Glucokinase
AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximatel...
T3104 Globalagliatin LY2608204 Glucokinase
Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
T26712 AZD-1656 AZD 1656 Glucokinase
AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2 diabetes.
T15159 Dorzagliatin HMS5552 Glucokinase
Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
T12056 MK-0941 free base Glucokinase
MK-0941 free base is an orally active glucokinase activator, exhibiting strong glucose-lowering activity and is a potential therapeutic agent for treatment of type 2 diabetes.
T19500 Palmitelaidic Acid trans-Palmitoleic acid,9-trans-Hexadecenoic acid Glucokinase , AMPK , PPAR
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.
T68762 LY-2599506
LY-2599506 is a novel glucokinase activator.
T30142 ARRY-403 AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151 Glucokinase
ARRY-403 is a novel glucokinase activator that reduces fasting and postprandial blood glucose in patients with type 2 diabetes.
T77784 WAY-297848 Glucokinase
WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.
T3104L (1S,2R)-Globalagliatin (1S,2R)-Globalagliatin(1S,2R-1234703-40-2) Glucokinase
(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.
T14212 AMG-1694 Glucokinase
AMG-1694, a potent disruptor of the glucokinaseglucokinase regulatory protein (GK-GKRP) complex, operates by promoting the dissociation of this complex, thereby indirectly enhancing GK enzymatic activity with an IC50 of...
T4726 D-Glucose 6-phosphate sodium G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate Others , Endogenous Metabolite
In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the begi...
T23765 AZD1092 AZD 1092,AZD-1092
AZD1092 is the glucokinase enzyme activator.
T25452 GKA-71 GKA 71
GKA-71 is an effective glucokinase activator (GKA).
T64046 BMS-820132
BMS-820132 is a glucokinase activator (AC50: 29 nM).
T5069 D-Glucose 6-phosphate potassium salt Others
D-Glucose 6-phosphate potassium is the potassiu salt form of D-glucose 6-phosphate, which is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
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TargetMol