Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Glucokinase activator 1 is a liver-directed glucokinase activator (EC50: 34 nM). |
Targets&IC50 | GK:(EC50)34 nM |
In vivo | The predominant liver-directed tissue distribution of Glucokinase activator 1 ensures a good safety window with respect to hypoglycemia over a 10-fold dose range.Glucokinase activator 1 (3 to 300 mg/kg, oral, 180 minutes) shows a dose dependent improvement in glucose excursion in oGTT in a DIO mouse model of T2D. |
Molecular Weight | 586.58 |
Formula | C27H20F2N2O7S2 |
CAS No. | 1328987-85-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Glucokinase activator 1 1328987-85-4 Others inhibitor inhibit