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Search Results for " ggf "

Targets

8

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T80101 Z-GGF-CMK Proteasome
Z-GGF-CMK, a protease inhibitor, impedes ClpP1P2 and proteasome activity and demonstrates cytotoxic effects on HepG2 cells, with a CC50 value of 125 μM [1].
T77891 Propargyl-PEG4-GGFG-DXd
Propargyl-PEG4-GGFG-DXd is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising an ADC linker and the DNA topoisomerase I inhibitor known as DXd [1].
T81833 MC-GGFG-AM-(10NH2-11F-Camptothecin)
MC-GGFG-AM-(10NH2-11F-Camptothecin) is an antibody-drug conjugate (ADC) that exhibits antitumor activity by targeting TROp-2 with the sacituzumab antibody through a hydrolysable, pH-sensitive linker. It is utilized in ca...
T16024 MC-GGFG-DX8951 Others
MC-GGFG-DX8951 is a drug-linker conjugate designed for antibody-drug conjugation (ADC) that demonstrates antitumor activity through the deployment of DX8951, a DNA topoisomerase I inhibitor, connected using the protease-...
T75134 MC-GGFG-AM-(10Me-11F-Camptothecin)
MC-GGFG-AM-(10Me-11F-Camptothecin) acts as a linker-payload conjugate in the synthesis of ZW251, an antibody-drug conjugate (ADC) designed to target human GPC3. This ADC comprises a humanized IgG1 antibody attached to ZD...
T77886 GGFG-amide-glycol-amide-Exatecan
Exatecan (Intermediate 2), a derivative of GGFG-amide-glycol-amide-Exatecan, facilitates the synthesis of antibody-drug conjugates (ADCs) [1].
T81834 MC-GGFG-(7ethanol-10NH2-11F-Camptothecin)
MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a protease-cleavable drug-linker conjugate utilized in antibody-drug conjugates (ADCs), featuring an MC-GGFG linker that allows for enzymatic cleavage [1].
T82323 GGFG-Eribulin
Eribulin-GGFG (Compound GGFG) is a drug-linker conjugate for antibody-drug conjugates (ADCs). Comprised of the cytotoxic agent exatecan and a connecting linker, it facilitates the synthesis of ADCs [1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00479 Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-05813 Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-00031 Neuregulin-1/NRG1 Protein, Human, Recombinant (His) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02720 NRG1 alpha Protein, Human, Recombinant (hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02721 NRG1 alpha Protein, Human, Recombinant (His) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-03010 NRG1 beta 1 Protein, Human, Recombinant Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02705 NRG1 beta 1 Protein, Human, Recombinant (hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPY-02719 NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) Human HEK293
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 rec...
TMPJ-00448 NRG1 beta 1 Protein, Human, Recombinant (aa 2-246) Human E. coli
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand f...
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