8
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6501 | Fludarabine Phosphate | NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis |
Fludarabine Phosphate (NSC 312887 Phosphate) is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidl... | |||
T1038 | Fludarabine | NSC 118218,Fludarabinum,F-ara-A | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , STAT |
Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation. Fludarabine has antitumor activity and can be used for the treatment of leukemia and... | |||
T19688 | Lodenosine | FddA,3'-dideoxyarabinosyladenine,Fddl,2'-F-dd-ara-A,2'-Fluoro-2',DDG-1 | |
Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV. | |||
T74032 | Ara-F-NAD+ sodium | ||
Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2]. | |||
TNU1422 | 2'-F-2'-ara-N2-ibu-dG Phosphoramidite | ||
2'-F-2'-ara-N2-ibu-dG Phosphoramidite is a Nucleoside Phosphoramidite. | |||
T38730 | Ara-F-NAD+ | ||
Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM. | |||
T13907 | Sulfo-ara-F-NMN | CZ-48 | Others |
Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NM... | |||
T74088 | Fludarabine triphosphate trisodium | ||
Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, acts as a potent, noncompetitive, and specific inhibitor of DNA primase, exhibiting an IC50 value of 2.3 μM and a Ki of 6.1 μM. It ... |