eyes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21445	Naphazoline	AK-Con,Naphcon-a,Clear Eyes,All Clear	Adrenergic Receptor
	Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.		Adrenergic Receptor
T6469	Dichlorphenamide	Diclofenamide,Daranide,Antidrasi	Carbonic Anhydrase
	Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.		Carbonic Anhydrase
T31738	Eyeseryl	Ac-beta-ala-his-ser-his-oh
	Eyeseryl, also known as Acetyl Tetrapeptide-5, humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity as well as overall smoothness.
T21371	Apraclonidine hydrochloride	Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum	Adrenergic Receptor
	Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco...		Adrenergic Receptor
T1223	Ceftriaxone sodium hydrate	Ceftriaxone Sodium Trihydrate,Ceftriaxone disodium hemiheptahydrate,Ceftriaxone sodium	Others , Antibacterial , Antibiotic
	Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.		Others , Antibacterial , Antibiotic
T15718	Latanoprost acid		GPR
	Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about low...		GPR
T3746	Dimethyl phthalate	Solvanom,Avolin,Fermine	Others
	Dimethyl phthalate (Fermine) has many uses, including in solid rocket propellants, plastics, and insect repellants. Acute (short-term) exposure to dimethyl phthalate, via inhalation in humans and animals, results in irri...		Others
T25482	H-0104 Dihydrochloride	H0104 Dihydrochloride,H0104 2HCl,H 0104 Dihydrochloride,H 0104 2HCl,H-0104 2HCl
	H-0104 Dihydrochloride is an inhibitor of ROCK that acts by applying potent intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
T10357	AR-13324 analog mesylate		Others
	AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.		Others
T25483	H-0106 Dihydrochloride	H 0106 2HCl,H0106 2HCl,H0106 Dihydrochloride
	H-0106 Dihydrochloride is an inhibitor of ROCK that acts by applying strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
T60350	Apraclonidine
	Apraclonidine (ALO 2145) is a selective α2 and weak α1 receptor agonist that effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine is a topical ophthalmic solution [1] [2].
T70763	KR-67607
	KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat ...
T10182	6-Hydroxybenzbromarone		Others
	6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 μM). It is an angiogenic agent, has strong inhibitory effects on cell migrat...		Others
T38194	Prostaglandin E3	PGE3
	Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid. [1] In human ocular tissue, it comprises 2.4% of the COX products formed. [1] When applied to the eyes of a rabbit, a ...
T38219	11-cis Retinal
	11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin. When 11-cis retinal absorbs a photon of light, it isomerizes to for...
T69623	Tridemorph
	Tridemorph is a sterol biosynthetic inhibitor. It is a fungicide used to control Erysiphe graminis. It was developed by BASF in the 1960s who use the trade name Calixin. The World Health Organization has categorized it a...
T71119	Netarsudil free base
	Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Hum...
T37613	Ibuprofen Carboxylic Acid
	Ibuprofen carboxylic acid is a major metabolite of ibuprofen . It prevents fructose-, cyanate-, and prednisolone-induced inactivation of catalase and fructose- and cyanate-induced inactivation of fumarase when used at a ...
T38196	Prostaglandin F2α isopropyl ester	Prostaglandin F2α isopropyl ester
	PGF2α isopropyl ester is an ester prodrug of PGF2α with enhanced lipid solubility. Due to better membrane penetration, PGF2α isopropyl ester is more suitable than PGF2α or PGF2α tromethamine salt for topical application ...
T31194	Dalapon	Basfapon B,Dowpon M,Dawpon-Rae
	Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occ...