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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1900 | LDN-212854 | LDN212854,BMP Inhibitor III | ALK , TGF-beta/Smad |
LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1/3 compared to other inhibitors. | |||
T77747 | Adecatumumab | MT 201 | Others |
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer. | |||
T16283 | Neocarzinostatin | 5-HT Receptor | |
Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic. It recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin leads to apoptosis. Neocarzinostatin has potenti... | |||
T76799 | Citatuzumab bogatox | ||
Citatuzumab bogatox (VB6-845) is a recombinant immunotoxin consisting of a humanized antibody's Fab fragment targeting EpCAM and a modified bouganin cytotoxin. It selectively binds to EpCAM-positive cell lines, inducing ... | |||
T76836 | Tucotuzumab | ||
Tucotuzumab (Anti-EPCAM Recombinant Antibody) is a protein composed of an IgG1 monoclonal antibody specific for the human Epithelial Cell Adhesion Molecule (EpCAM) antigen, linked to two molecules of IL-2 . Tucotuzumab i... | |||
T78307 | Catumaxomab | ||
Catumaxomab, a trifunctional IgG2 antibody with mouse and rat heavy and light chain components, targets human EpCAM and CD3 receptors. Its Fc region exhibits affinity for FcγRI (CD64), FcγRIIA (CD32a), and FcγRIII (CD16)... | |||
T76996 | Solitomab | ||
Solitomab (AMG 110), a bispecific antibody targeting CD3 and EpCAM, is utilized in researching primary uterine and ovarian carcinosarcoma cancer [1] [2]. |