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Search Results for " endothelin-2 "

15

Compounds

Cat No. Product Name Synonyms Targets
TP1174 Endothelin-2 (49-69), human Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine) Others
Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.
TP2143 Endothelin-2 (49-69), human TFA Endothelin-2 (49-69) (human, canine) TFA,Human endothelin-2 TFA Others
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.
T6258 Zibotentan ZD4054 Apoptosis , Endothelin Receptor
Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
T7817 Aprocitentan ACT-132577 Endothelin Receptor
Aprocitentan (ACT-132577) is ETA and ETB antagonist .
T7391 SAR407899 ROCK , Rho
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
T6792 BQ-123 BQ123 Endothelin Receptor
BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.
TP2246 Endothelin-1 (1-15), amide, human Others
Endothelin-1 is one of the there isoforms of endothelin (identified as ET-1, -2, -3) with varying regions of expression and binding to at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC.
T61498 Sulfisoxazole diethanolamine
Sulfisoxazole diethanolamine, also known as Sulfafurazole diethanolamine, is a sulfonamide antibacterial compound with an oxazole substituent. It acts as an endothelin receptor antagonist, specifically targeting endothel...
T36007 Nebentan
Nebentan (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan . Nebentan inhibits [125I] endothelin-1 binding to cloned human endothelin ETA...
T9621 N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Methylpyridine-2-sulfonamide Others
N-(6-chloro-5-(2-Methoxyphenoxy)-2-(pyridin-4-yl)pyriMidin-4-yl)-5-Met inhibits endothelin binding to membranes from CHO cells carrying human ETA receptor and human ETB receptor with IC50 of 268nM and 1810nM, respectivel...
T73877 BQ-123 TFA
BQ-123 TFA, a potent and selective endothelin A (ETA) receptor antagonist, demonstrates an IC50 of 7.3 nM and a Ki of 25 nM. It effectively inhibits endothelin-1-induced proliferation of human pulmonary artery smooth mus...
T76305 [Ala2] Endothelin-3, human
[Ala2] Endothelin-3, human is a linear analog of endothelin-3 (ET-3), characterized by the substitution of Ala for Cys residues. ET-3, a vasoactive peptide produced by human rhabdomyosarcoma cell lines but not expressed ...
T38167 BE-24566B
BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, an...
T14068 A-192621 Others
A-192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. A-192621 promotes apoptosis in PASMCs and it also causes elevation of arteri...
T78096 BQ-3020 ammonium Endothelin Receptor
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2 nM and induces vasoconstriction in rabbit pulmonary arterie...
TargetMol