epha3 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38511	AWL-II-38.3		Ephrin Receptor
	AWL-II-38.3 is a highly effective inhibitor of EphA3, a receptor for ephrin-A. It demonstrates potent kinase inhibitory activity against EphA3 and does not show significant cellular activity against Src-family kinases or...		Ephrin Receptor
T4349	Sitravatinib	MG516,MGCD516	Discoidin Domain Receptor (DDR) , VEGFR , FLT , Trk receptor , TAM Receptor , c-Kit , Ephrin Receptor
	Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and Axl.
T77031	Ifabotuzumab
	Ifabotuzumab (KB004), an IgG1κ antibody, specifically binds to EphA3 (K D =610 pM), inducing tumor cell apoptosis, activating antibody-dependent cell-mediated cytotoxicity (ADCC), and damaging tumor vasculature. Addition...
T74642	DB1113
	DB1113 (Example 24) is a bifunctional compound designed for the targeted degradation of various kinases. It effectively degrades a range of kinases, including ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, M...
T73368	UniPR505		Ephrin Receptor
	UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.		Ephrin Receptor
T74644	DB0614
	DB0614 (Example 21) is a bifunctional compound designed for the targeted degradation of kinases, effectively breaking down a wide array of kinases including AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK...

Compounds

AWL-II-38.3

T38511

Synonym:

Target: Ephrin Receptor

Sitravatinib

T4349

Synonym: MG516,MGCD516

Target: Discoidin Domain Receptor (DDR), VEGFR, FLT, Trk receptor, TAM Receptor, c-Kit, Ephrin Receptor

Target: Ephrin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-01387	EPhA3 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude...
TMPY-02562	EphA3 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	EphA3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.2 kDa and the accession number is A6K4V7.
TMPY-04082	EphA3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	EphA3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.7 kDa and the accession number is Q8BRB1.
TMPY-00631	EphA3 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	EphA3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 85.8 kDa and the accession number is A6K4V7.
TMPY-03275	EphA3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EphA3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.3 kDa and the accession number is A0A140VJJ0.
TMPY-02493	EphA3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	EphA3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.2 kDa and the accession number is Q8BRB1.
TMPY-04448	EphA3 Protein, Mouse, Recombinant (aa 569-984)	Mouse	Baculovirus Insect Cells
	EphA3 Protein, Mouse, Recombinant (aa 569-984) is expressed in Baculovirus insect cells. The predicted molecular weight is 46.6 kDa and the accession number is EDK98238.1.
TMPY-04447	EphA3 Protein, Mouse, Recombinant (aa 569-984, His & GST)	Mouse	Baculovirus Insect Cells
	EphA3 Protein, Mouse, Recombinant (aa 569-984, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.3 kDa and the accession number is EDK98238.1.
TMPJ-00085	EFNA4 Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Ephrin-A4 is a member of the ephrin ligand family which binds members of the Eph receptor family. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor binding domain. Ephrin...
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle,...
TMPJ-00224	EFNB2 Protein, Mouse, Recombinant (hFc & His)	Mouse	HEK293 Cells
	Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors...