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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T74512 | PROTAC eEF2K degrader-1 | ||
PROTAC eEF2K degrader-1 (Compound 11l), an eEF2K-targeting PROTAC small molecule, effectively induces apoptosis in MDA-MB-231 cells through mediating eEF2K degradation [1]. | |||
TQ0137 | A-484954 | A 484954 | CaMK , Parasite , Autophagy |
A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor. | |||
T6605 | NH125 | CaMK , Virus Protease , PKA , Antibacterial , PKC , Autophagy , Antifungal | |
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor. | |||
T73224 | AMPK-IN-1 | ||
AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM. It induces phosphorylation of eEF2 independent of the mTORC1 pathway. | |||
T70431 | TX-1123 | ||
TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for C... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01286 | EEF2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly form... | |||
TMPH-01970 | EEF2KMT Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'. EEF2KMT Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is ... |