12
9
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62560 | Sirpiglenastat | DRP-104 | Glutaminase |
Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by inhibiting glutamine metabolism and stimulating the innate and adaptive immune system. | |||
T9617 | RdRP-IN-2 | SARS-CoV | |
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavirus (FIPV) replication. | |||
T24040 | ERDRP-0519 | ERDRP0519,ERDRP 0519 | Antiviral |
ERDRP-0519 is an orally bioavailable small-molecule inhibitor of the Measles virus (MeV) polymerase. It effectively prevents measles disease in squirrel monkeys (Saimiri sciureus) and exhibits potent inhibition of morbil... | |||
T73456 | DRP1i27 | ||
DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and ... | |||
T79233 | RdRP-IN-6 | DNA/RNA Synthesis | |
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM. It has potential applications in antiviral and anticancer research [1]. | |||
T73323 | RdRP-IN-5 | Influenza Virus | |
RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1]. | |||
T62687 | Drp1-IN-1 | ||
Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM). | |||
T40267 | RdRP-IN-3 | ||
RdRP-IN-3, a potential anti-influenza drug candidate, functions by inhibiting the activity of RNA-dependent RNA polymerase (RdRp). | |||
T72896 | Cis-RdRP-IN-5 | ||
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research. | |||
T79234 | RdRP-IN-7 | SARS-CoV | |
RdRP-IN-7, a RNA-dependent RNA polymerase (RdRp) inhibitor, demonstrates efficacy against SARS-CoV-2 infection with an inhibitory concentration (IC50) of 8.2 μM and (IC90) of 14.1 μM, alongside a cytotoxic concentration ... | |||
T62812 | RdRP-IN-4 | ||
RdRP-IN-4 (compound 11q) is an arylbenzohydrazide analogue, an orally active inhibitor of influenza A virus RNA-dependent RNA polymerase (RdRp) that directly binds the PB1 subunit of RdRp. RdRP-IN-4 inhibited H1N1 (A/PR/... | |||
T72792 | Trans-RdRP-IN-5 | ||
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01229 | DPYSL5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May have a function in neuronal differentiation and/or axon growth. | |||
TMPH-01210 | DENR Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
DENR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.0 kDa and the accession number is O43583. | |||
TMPH-01227 | DPYSL2 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the... | |||
TMPH-01226 | CRMP1 Protein, Human, Recombinant | Human | E. coli |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F... | |||
TMPH-01228 | DPYSL3 Protein, Human, Recombinant (His) | Human | E. coli |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. | |||
TMPY-06071 | SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) | SARS-CoV-2 | Baculovirus Insect Cells |
SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1. | |||
TMPJ-00792 | DNA PolymeraseBeta Protein, Human, Recombinant (His) | Human | E. coli |
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p... | |||
TMPH-02315 | XRCC5 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a... | |||
TMPH-02314 | XRCC5 Protein, Human, Recombinant (His & MBP) | Human | Baculovirus Insect Cells |
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a... |