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Search Results for " drp "

Targets

12

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T62560 Sirpiglenastat DRP-104 Glutaminase
Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by inhibiting glutamine metabolism and stimulating the innate and adaptive immune system.
T9617 RdRP-IN-2 SARS-CoV
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavirus (FIPV) replication.
T24040 ERDRP-0519 ERDRP0519,ERDRP 0519 Antiviral
ERDRP-0519 is an orally bioavailable small-molecule inhibitor of the Measles virus (MeV) polymerase. It effectively prevents measles disease in squirrel monkeys (Saimiri sciureus) and exhibits potent inhibition of morbil...
T73456 DRP1i27
DRP1i27, a potent human dynamin-related protein 1 (Drp1) inhibitor, targets the GTPase site of Drp1, forming hydrogen bonds with Gln34 and Asp218. It mitigates Drp1-mediated mitochondrial fission in cell line models and ...
T79233 RdRP-IN-6 DNA/RNA Synthesis
RdRP-IN-6 (compound 27) is an inhibitor of RNA-dependent RNA polymerase (RdRp), exhibiting an IC90 value of 14.1 μM. It has potential applications in antiviral and anticancer research [1].
T73323 RdRP-IN-5 Influenza Virus
RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].
T62687 Drp1-IN-1
Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).
T40267 RdRP-IN-3
RdRP-IN-3, a potential anti-influenza drug candidate, functions by inhibiting the activity of RNA-dependent RNA polymerase (RdRp).
T72896 Cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.
T79234 RdRP-IN-7 SARS-CoV
RdRP-IN-7, a RNA-dependent RNA polymerase (RdRp) inhibitor, demonstrates efficacy against SARS-CoV-2 infection with an inhibitory concentration (IC50) of 8.2 μM and (IC90) of 14.1 μM, alongside a cytotoxic concentration ...
T62812 RdRP-IN-4
RdRP-IN-4 (compound 11q) is an arylbenzohydrazide analogue, an orally active inhibitor of influenza A virus RNA-dependent RNA polymerase (RdRp) that directly binds the PB1 subunit of RdRp. RdRP-IN-4 inhibited H1N1 (A/PR/...
T72792 Trans-RdRP-IN-5
Trans-RdRP-IN-5 is a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), with applications in influenza virus research.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01229 DPYSL5 Protein, Human, Recombinant (His & Myc) Human E. coli
May have a function in neuronal differentiation and/or axon growth.
TMPH-01210 DENR Protein, Human, Recombinant (His & SUMO) Human E. coli
DENR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.0 kDa and the accession number is O43583.
TMPH-01227 DPYSL2 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the...
TMPH-01226 CRMP1 Protein, Human, Recombinant Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F...
TMPH-01228 DPYSL3 Protein, Human, Recombinant (His) Human E. coli
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
TMPY-06071 SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 108.3 kDa and the accession number is YP_009725307.1.
TMPJ-00792 DNA PolymeraseBeta Protein, Human, Recombinant (His) Human E. coli
Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base excision repair. Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-p...
TMPH-02315 XRCC5 Protein, Human, Recombinant (His & Myc) Human E. coli
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
TMPH-02314 XRCC5 Protein, Human, Recombinant (His & MBP) Human Baculovirus Insect Cells
Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a...
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