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Cat No. | Product Name | Synonyms | Targets |
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T39527 | Se-DMC | ||
Se-DMC effectively reduces the inflammatory response, nociception, and neurobehavioral deficits induced by complete Freund's adjuvant (CFA) in mice. | |||
T8550 | NDMC101 | Others , NF-κB , Proteasome | |
NDMC101 is an inhibitor of dipeptidyl peptidase-IV activity in human T cells and exhibits immunomodulatory effects. It also acts as a novel inhibitor of NFATc1 and NF-κB activity. | |||
T11061 | DMCM hydrochloride | GABA Receptor | |
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor subtypes. For α1, α2, α3, and α5 receptors, their Kis were 10 ... | |||
T13657 | dMCL1-2 | Others | |
dMCL1-2 is a potent and selective myeloid leukemia 1 (MCL1) degrading agent based on PROTAC, which binds to MCL1 with a KD of 30 nM. dmcl-2 activates the apoptosis mechanism by degrading MCL1. | |||
T35610 | 2,5-dimethyl Celecoxib | Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor | |
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ... |
Cat No. | Product Name | Species | Expression System |
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TMPY-04984 | CXCL17 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with bre... |