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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1272 | Cytarabine | Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine | Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV |
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity. | |||
T1272L | Cytarabine hydrochloride | Ara-C hydrochloride,Cytosine Arabinoside hydrochloride | DNA/RNA Synthesis |
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... | |||
T38718 | Cytarabine triphosphate | Cytarabine triphosphate,Ara-CTP | |
Cytarabine triphosphate (Ara-CTP), a competitive inhibitor of DNA synthesis and an active metabolite of Cytarabine, exhibits predictive potential for leukemic blasts' chemosensitivity to Cytarabine through intracellular ... | |||
T15009 | Elacytarabine | 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055 | Others |
Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors. | |||
T31088 | CPX-351 | Cytarabine/daunonubicin,Vyxeos,CPX 351,Daunonubicin/cytarabine | |
CPX-351 is a Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs). | |||
T15343 | Fosteabine | YNK 01,Cytarabine ocfosfate | Others |
Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase. | |||
T29643 | Adamantoylcytarabine | Adamantoyl cytarabine,Adam CA | |
Adamantoylcytarabine is abioactive chemical. | |||
T1591 | Ancitabine hydrochloride | NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C | Others , DNA/RNA Synthesis , Autophagy |
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytar... | |||
T27342L | Flurocitabine HCl | Flurocitabine HCl(37717-21-8 Free base) | Others |
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocit... | |||
T79224 | Ara-SH | Apoptosis | |
Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded Cytarabine and Venetoclax nanoparticle (AV-NP), demonstrating notable syn... | |||
T21161 | Ancitabine | ||
Ancitabine, a congener of cyterabine, is metabolized to cytarabine, thereby maintains a more constant antineoplastic action. | |||
T11956L | MBC-11 | Others | |
MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). It also has the potential to treat tumor-induced bone disease (TIBD). | |||
T11956 | MBC-11 triethylamine | Others | |
MBC-11 triethylamine has potential to treat tumor-induced bone disease (TIBD), is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). | |||
T71654 | APcK110 | ||
APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1.2 and the SCF-responsive cell line OCI/AML3 in a dose-dependent manner . APcK110 is a more potent inhibitor of OCI/AML3... | |||
T68917 | Fazarabine | ||
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph... |