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Search Results for " cytarabine "

15

Compounds

Cat No. Product Name Synonyms Targets
T1272 Cytarabine Ara-C,Cytosine Arabinoside,Cytosine β-D-arabinofuranoside,Arabinocytidine Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , HSV
Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM). Cytarabine inhibits DNA polymerase and induces cell cycle arrest, autophagy, and apoptosis. Cytarabine has antitumor activity.
T1272L Cytarabine hydrochloride Ara-C hydrochloride,Cytosine Arabinoside hydrochloride DNA/RNA Synthesis
Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ...
T38718 Cytarabine triphosphate Cytarabine triphosphate,Ara-CTP
Cytarabine triphosphate (Ara-CTP), a competitive inhibitor of DNA synthesis and an active metabolite of Cytarabine, exhibits predictive potential for leukemic blasts' chemosensitivity to Cytarabine through intracellular ...
T15009 Elacytarabine 5'-Oleoyl cytosine arabinoside,5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine,5'-Oleoyl cytarabine,CP 4055 Others
Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
T31088 CPX-351 Cytarabine/daunonubicin,Vyxeos,CPX 351,Daunonubicin/cytarabine
CPX-351 is a Liposomal-encapsulated combination of daunorubicin and cytarabine for the treatment of newly diagnosed tAML or AML with myelodysplasia-related changes (AML-MRCs).
T15343 Fosteabine YNK 01,Cytarabine ocfosfate Others
Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.
T29643 Adamantoylcytarabine Adamantoyl cytarabine,Adam CA
Adamantoylcytarabine is abioactive chemical.
T1591 Ancitabine hydrochloride NSC 145668 HCl,Cyclocytidine hydrochloride,Cyclo-CMP hydrochloride,Cyclocytidine HCl,Cyclo-C Others , DNA/RNA Synthesis , Autophagy
Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytar...
T27342L Flurocitabine HCl Flurocitabine HCl(37717-21-8 Free base) Others
Flurocitabine HCl is a fluorinated anhydride analog of cytarabine, which is partially hydrolyzed in vivo to two active antitumor substances (arabinosyl-fluorouracil (ara-FC) and arabinosyl-fluorouracil (ara-FU)).Flurocit...
T79224 Ara-SH Apoptosis
Ara-SH, a derivative of Cytarabine with a mercaptopropionic acid substitution, serves as the initiator for the self-assembly of a smart, co-loaded Cytarabine and Venetoclax nanoparticle (AV-NP), demonstrating notable syn...
T21161 Ancitabine
Ancitabine, a congener of cyterabine, is metabolized to cytarabine, thereby maintains a more constant antineoplastic action.
T11956L MBC-11 Others
MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). It also has the potential to treat tumor-induced bone disease (TIBD).
T11956 MBC-11 triethylamine Others
MBC-11 triethylamine has potential to treat tumor-induced bone disease (TIBD), is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC).
T71654 APcK110
APcK110 is a novel Kit inhibitor . APcK110 inhibits proliferation of the mastocytosis cell line HMC1.2 and the SCF-responsive cell line OCI/AML3 in a dose-dependent manner . APcK110 is a more potent inhibitor of OCI/AML3...
T68917 Fazarabine
Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is ph...
TargetMol