cav3.2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0928	L-Ascorbic acid	Vitamin C,Ascorbic acid,L(+)-Ascorbic acid,L-Ascorbate	Apoptosis , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-...
T6674	L-Ascorbic acid sodium salt	(+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,Sodium L-ascorbate	Apoptosis , Others , Calcium Channel , Reactive Oxygen Species , Endogenous Metabolite
	L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.
T8944	TTA-A2		Calcium Channel
	TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ...		Calcium Channel
T12076	ML218 hydrochloride		Others
	ML218 hydrochloride is a selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor (Cav3.2 and Cav3.3 with IC50s of 310 nM and 270 nM , respectively).		Others
T12076L	ML218		Calcium Channel
	ML218 is an orally active, selective, potent, and blood-brain barrier-crossing inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) (IC50 for Cav3.2 and Cav3.3 is 310 nM and 270 nM, respectively).ML218 inhibits the...		Calcium Channel
T63350	Cav 3.2 inhibitor 3
	Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.
T62586	Cav 2.2/3.2 blocker 1
	Cav 2.2/3.2 blocker 1 (Compound 9e) is a neuronal calcium channel blocker that acts on Cav2.2 (IC50: 1.22 μM) and Cav3.2 (IC50: 80 μM). Can penetrate the central nervous system.
T64203	T-Type calcium channel inhibitor 2
	T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, acting on Cav3.1 (α1G) (IC50: 31.0 μM), Cav3.2 (α1H) (IC50: 83.1 μM), Cav3.3 (α1I) (α1H) ( T-Type calcium channel inhi...
T63606	Cav 3.2 inhibitor 2
	Cav 3.2 inhibitor 2 is an inhibitor of Cav3.2 T-type Ca2+channels with an IC50=0.09339 μM at a constant potential of -80 mV. Cav 3.2 inhibitor 2 exhibits potent inhibition of T-channel-dependent somatic and visceral pain...
TP2003	Mambalgin 1
	Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively). Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2...
T75954	Mambalgin 1 TFA
	Mambalgin 1 TFA, a selective inhibitor of ASIC1a (with IC50 values of 192 nM for human ASIC1a and 72 nM for the ASIC1a/1b dimer), preferentially binds to the channel in its closed/inactive state. It demonstrates selectiv...
T36070	(±)5(6)-EET
	5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5...
T79195	Cav 3.2 inhibitor 4		Calcium Channel
	Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an IC50 value of 0.6 μM. It is utilized in atrial fibrillation res...		Calcium Channel