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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T18868 | Val-Cit | Others | |
Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs). | |||
T4678 | Fmoc-Val-Cit-PAB | Others | |
Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC). | |||
T18867 | Val-Cit-PAB-MMAE | ||
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat... | |||
T17691 | Boc-Val-Cit-OH | Others | |
Boc-Val-Cit-OH is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T17693 | Boc-Val-Cit-PAB | Others | |
Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs). | |||
T17213 | Val-cit-PAB-OH | Others | |
Val-cit-PAB-OH is an ADC linker that is cleavable. | |||
T7767 | FMoc-Val-Cit-PAB-PNP | Others | |
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). | |||
T18321 | Mc-Val-Cit-PAB-Cl | Others | |
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5... | |||
T5149 | MC-Val-Cit-PAB | Others , AChR | |
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker. | |||
T17983 | Fmoc-Val-Cit-PAB-MMAE | Others | |
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. | |||
T17692 | Boc-Val-Cit-PAB-PNP | Others | |
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T18267 | Mal-PEG1-Val-Cit-OH | Others | |
Mal-PEG1-Val-Cit-OH is a cleavable one-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T40303 | 5-A-RU-PABC-Val-Cit-Fmoc | Others | |
5-A-RU-PABC-Val-Cit-Fmoc is one of the precursors of 5-A-RU, a small molecule mucosal-associated MAIT activator that is a precursor for bacterial synthesis of riboflavin. | |||
T3503 | MC-Val-Cit-PABC-PNP | Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate | Others , AChR |
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr... | |||
T77847 | MC-Val-Cit-PAB-Exatecan | MC-Val-Cit-PAB-DX8951 | |
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a conjugate of the DNA topoisomerase I inhibitor DX-8951 and a cathepsin-cleavable antibody-drug conjugate (ADC) linker, designed for targeted cancer therapy application... | |||
T38739 | Mal-PEG2-Val-Cit-PABA-PNP | Mal-PEG2-Val-Cit-PABA-PNP | |
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs). | |||
T77876 | Py-MAA-Val-Cit-PAB-MMAE | AAJ8D6-PY-Val-Cit-MMAE | |
Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lys... | |||
T39307 | Azido-PEG4-Val-Cit-PAB-MMAE | Azido-PEG4-Val-Cit-PAB-MMAE | |
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Az... | |||
T39765 | Mal-PEG1-Val-Cit-PAB-PNP | Mal-PEG1-Val-Cit-PAB-PNP | |
Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage. | |||
T39748 | DBCO-PEG4-Val-Cit-PAB-MMAF | DBCO-PEG4-Val-Cit-PAB-MMAF | |
DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin pol... |