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Search Results for " cit "

20

Compounds

Cat No. Product Name Synonyms Targets
T18868 Val-Cit Others
Val-Cit is a cleavable ADC linker. Val-Cit is used in the synthesis of antibody-drug conjugates (ADCs).
T4678 Fmoc-Val-Cit-PAB Others
Fmoc-Val-Cit-PAB is a linker for antibody-drug-conjugation (ADC).
T18867 Val-Cit-PAB-MMAE
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat...
T17691 Boc-Val-Cit-OH Others
Boc-Val-Cit-OH is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
T17693 Boc-Val-Cit-PAB Others
Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs).
T17213 Val-cit-PAB-OH Others
Val-cit-PAB-OH is an ADC linker that is cleavable.
T7767 FMoc-Val-Cit-PAB-PNP Others
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC).
T18321 Mc-Val-Cit-PAB-Cl Others
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC5...
T5149 MC-Val-Cit-PAB Others , AChR
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
T17983 Fmoc-Val-Cit-PAB-MMAE Others
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
T17692 Boc-Val-Cit-PAB-PNP Others
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis.
T18267 Mal-PEG1-Val-Cit-OH Others
Mal-PEG1-Val-Cit-OH is a cleavable one-unit polyethylene glycol (PEG) linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T40303 5-A-RU-PABC-Val-Cit-Fmoc Others
5-A-RU-PABC-Val-Cit-Fmoc is one of the precursors of 5-A-RU, a small molecule mucosal-associated MAIT activator that is a precursor for bacterial synthesis of riboflavin.
T3503 MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate Others , AChR
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr...
T77847 MC-Val-Cit-PAB-Exatecan MC-Val-Cit-PAB-DX8951
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a conjugate of the DNA topoisomerase I inhibitor DX-8951 and a cathepsin-cleavable antibody-drug conjugate (ADC) linker, designed for targeted cancer therapy application...
T38739 Mal-PEG2-Val-Cit-PABA-PNP Mal-PEG2-Val-Cit-PABA-PNP
Mal-PEG2-Val-Cit-PABA-PNP is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs).
T77876 Py-MAA-Val-Cit-PAB-MMAE AAJ8D6-PY-Val-Cit-MMAE
Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties. By targeting TRAILR2, Zapadcine-3a is internalized into the lys...
T39307 Azido-PEG4-Val-Cit-PAB-MMAE Azido-PEG4-Val-Cit-PAB-MMAE
Azido-PEG4-Val-Cit-PAB-MMAE is a drug-linker conjugate for antibody-drug conjugates (ADCs), comprising the anti-mitotic agent monomethyl auristatin E (MMAE, a tubulin inhibitor), connected through the cleavable linker Az...
T39765 Mal-PEG1-Val-Cit-PAB-PNP Mal-PEG1-Val-Cit-PAB-PNP
Mal-PEG1-Val-Cit-PAB-PNP is an ADC linker employed in the synthesis of ADCs, enabling cleavage.
T39748 DBCO-PEG4-Val-Cit-PAB-MMAF DBCO-PEG4-Val-Cit-PAB-MMAF
DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin pol...
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