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Search Result

Search Results for " cgrp "

Targets

CGRP Receptor Others

50

Compounds

2

Natural Products

11

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP2044L α-CGRP (human) acetate α-CGRP (human) acetate (90954-53-3 free base) Others
α-CGRP (human) acetate is a regulatory neuropeptide of 37 amino acids. It is the most potent vasodilator known to date and has inotropic and chronotropic effects.
TP2233L CGRP (rat) acetate Others
CGRP (rat) acetate is a calcitonin gene-related peptide (CGRP). CGRP (rat) acetate is a potent vasodilator.
T13453 CGRP antagonist 1 CGRP Receptor
CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases.
TP1323 CGRP 8-37 (rat) CGRP Receptor
CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.
TP1200 CGRP (83-119), rat TFA Calcitonin Gene Related Peptide(83-119), rat TFA Others
CGRP (83-119), rat TFA (Calcitonin Gene Related Peptide(83-119), rat TFA) is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1130 β-CGRP, human CGRP-II (Human),Human β-CGRP
β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular and nervous systems. β-CGRP contains a disulphide bridge at th...
TP2233 α-CGRP, rat CGRP (rat) Others
Endogenous neuropeptide, potent vasodilator
TP2044 α-CGRP(human) α-CGRP (human)
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.
TP1203 CGRP(83-119), rat Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Calcitonin Gene Related Peptide (CGRP) (83-119), rat is a 37 amino acid calcitonin family of neuropeptide, acts through calcitonin receptor-like receptor.
TP1202 Calcitonin Gene Related Peptide (CGRP) II, rat CGRP II, rat
Calcitonin Gene Related Peptide II is a potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
TP1131 β-CGRP, human TFA (101462-82-2 free base) CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and...
TP1201 CGRP II, rat (TFA) (99889-63-1 free base) Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Calcitonin Gene Related Peptide (CGRP) II, rat (TFA) is a neuropeptide with 37 amino acid.
T38190 Tyr-α-CGRP (rat) (trifluoroacetate salt)
Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.
T36555 Tyr-α-CGRP (human) (trifluoroacetate salt)
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti...
T75978 β-CGRP, human TFA
Human β-CGRP TFA (β-CGRP, human TFA) is a calcitonin peptide that functions through interaction with the calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP) complex, demonstrating IC50...
T75788 α-CGRP(human) TFA
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as a potent vasodilator [1].
T75732 α-CGRP, rat TFA
α-CGRP, rat TFA, a neuropeptide (calcitonin gene-related peptide (CGRP)) mainly expressed in neuromuscular junction, is a potent vasodilator. α-CGRP, rat TFA can lead to a fall in blood pressure and an increase in heart ...
TP1134 HCGRP-(8-37) Human α-CGRP (8-37)
Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist
T78540 α-CGRP (mouse, rat) TFA CGRP Receptor
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and functions as a potent vasodilator. Peripheral administration...
T76032 Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Calcitonin Gene-Related Peptide (CGRP) II, rat TFA, functions as a potent and enduring vasodilator by activating CGRP receptors. This compound is utilized in cardiovascular disease research [1].
T8682 Vazegepant hydrochloride Vazegepant HCl CGRP Receptor
Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.
T17194 Ubrogepant MK-1602 CGRP Receptor
Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.
TP1040 Calcitonin (salmon) Calcitonin salmon,Salmon calcitonin CGRP Receptor
Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.
T12293L Olcegepant BIBN-4096,BIBN 4096BS CGRP Receptor
Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP).
T4610 Rimegepant BMS 927711,BMS-927711,BMS927711,BHV-3000 CGRP Receptor
Rimegepant (BMS 927711) is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.
T6590 MK-3207 Hydrochloride MK-3207 HCl CGRP Receptor
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.
TP1134L HCGRP-(8-37) acetate HCGRP-(8-37) acetate (119911-68-1 free base) CGRP Receptor
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.
T76682 Galcanezumab LY 2951742 CGRP Receptor
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches.
T76874 Erenumab AMG-334 CGRP Receptor
Erenumab is a whole-human monoclonal antibody. Erenumab inhibits calcitonin gene-related peptide (CGRP) receptors. Erenumab can be used to prevent migraine attacks.
TP1257L Adrenomedullin (AM) (22-52), human acetate Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base） CGRP Receptor
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an adrenomedullin receptor.
T16093 Telcagepant MK-0974 Others
Telcagepant is an orally active antagonist of calcitonin gene-related peptide (CGRP) receptor (Kis: 0.77 nM and 1.2 nM for human and rhesus CGRP receptors, respectively).
T12293 Olcegepant hydrochloride BIBN-4096 hydrochloride,BIBN4096BS hydrochloride Others
Olcegepant hydrochloride is a potent and selective non-peptidethe calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (with IC50 of 0.03 nM for human CGRP).
T70820 MK-8825
MK-8825 is a CGRP receptor antagonist.
T76363 [Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
[Tyr22] Calcitonin Gene Related Peptide (22-37), rat, refers to a fragment (amino acids 22-37) of the rat calcitonin gene-related peptide (CGRP) that targets the CGRP receptor and adenylate cyclase. While calcitonin is p...
T38734 Vazegepant Zavegepant,BHV-3500
Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.
T30537 BMS-694153 BMS694153,BMS 694153
BMS-694153 is a potent and selective CGRP receptor antagonist.
T71246 DD04107
DD04107 is a novel inhibitor of α-calcitonin gene-related peptide (α-CGRP) exocytotic release from primary sensory neurons, selectively interacting with Synaptotagmin 1.
T39522 HTL22562
HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.
T73703 (3R,5R,6S)-Atogepant
Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of itself and serves as a calcitonin gene-related peptide (CGRP) receptor antagonist, primarily utilized in migraine research.
T26796 BI-44370
BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.
T76680 Fremanezumab
Fremanezumab (TEV-48125), a humanized IgG2a monoclonal antibody, potently and selectively targets the calcitonin gene-related peptide (CGRP), a 37-amino acid neuropeptide implicated in the central and peripheral mechanis...
T76473 Adrenotensin (human)
Adrenotensin (human) (Pro-ADM-153-185 (human)), a 153-185 fragment of the Adrenomedullin precursor peptide, is part of the Multifunctional Adrenomedullin (ADM). This 52-amino acid peptide, a member of the CGRP superfamil...
T21558 MK-3207
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep...
T70837 Rimegepant sulfate hydrate
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown ...
T76678 Eptinezumab
Eptinezumab, a human monoclonal antibody, specifically binds to and blocks the calcitonin gene-related peptide (CGRP) from binding to its receptor, thus acting as a preventive treatment for migraine in adults [1].
T27025 Cizolirtine citrate E-4018,E4018,E 4018
Cizolirtine is a calcitonin gene-related peptide antagonist. Cizolirtine may be useful for alleviating some neuropathic somatosensory disorders, in particular cold allodynia, with a reduced risk of undesirable side effec...
TP1232 Amylin, amide, rat Amylin (rat)
Amylin is a peptide that displays 50% homology with calcitonin gene-related peptide (CGRP), Amylin is colocalized with somatostatin in endocrine cells of the gastric fundus. In isolated mouse stomach, amylin caused a con...
TP2049 CRSP-1
Endogenous central calcitonin (CT) receptor agonist that stimulates cAMP formation at a potency 350-fold greater than CT (ED50 values are 0.2 and 71 nM respectively). Displays no activity at calcitonin-gene related pepti...
T75934 AC 187 TFA
AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM. It demonstrates greater selectivity for the amylin receptor over calcitonin and CGRP receptors and has ...
T37476 Cyclo(L-Phe-L-Val)
Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It indu...

Compounds

α-CGRP (human) acetate
TP2044L
Synonym: α-CGRP (human) acetate (90954-53-3 free base)
Target: Others
CGRP (rat) acetate
TP2233L
Synonym:
Target: Others
CGRP antagonist 1
T13453
Synonym:
Target: CGRP Receptor
CGRP 8-37 (rat)
TP1323
Synonym:
Target: CGRP Receptor
CGRP (83-119), rat TFA
TP1200
Synonym: Calcitonin Gene Related Peptide(83-119), rat TFA
Target: Others
β-CGRP, human
TP1130
Synonym: CGRP-II (Human),Human β-CGRP
Target:
α-CGRP, rat
TP2233
Synonym: CGRP (rat)
Target: Others
α-CGRP(human)
TP2044
Synonym: α-CGRP (human)
Target:
CGRP(83-119), rat
TP1203
Synonym: Calcitonin Gene Related Peptide (CGRP) (83-119), rat
Target:
Calcitonin Gene Related Peptide (CGRP) II, rat
TP1202
Synonym: CGRP II, rat
Target:
β-CGRP, human TFA (101462-82-2 free base)
TP1131
Synonym: CGRP-II (Human) (TFA),Human β-CGRP (TFA),β-CGRP, human TFA
Target:
CGRP II, rat (TFA) (99889-63-1 free base)
TP1201
Synonym: Calcitonin Gene Related Peptide (CGRP) II, rat (TFA),CGRP II, rat (TFA)
Target:
Tyr-α-CGRP (rat) (trifluoroacetate salt)
T38190
Synonym:
Target:
Tyr-α-CGRP (human) (trifluoroacetate salt)
T36555
Synonym:
Target:
β-CGRP, human TFA
T75978
Synonym:
Target:
α-CGRP(human) TFA
T75788
Synonym:
Target:
α-CGRP, rat TFA
T75732
Synonym:
Target:
HCGRP-(8-37)
TP1134
Synonym: Human α-CGRP (8-37)
Target:
α-CGRP (mouse, rat) TFA
T78540
Synonym:
Target: CGRP Receptor
Calcitonin Gene Related Peptide (CGRP) II, rat TFA
T76032
Synonym:
Target:
Vazegepant hydrochloride
T8682
Synonym: Vazegepant HCl
Target: CGRP Receptor
Ubrogepant
T17194
Synonym: MK-1602
Target: CGRP Receptor
Calcitonin (salmon)
TP1040
Synonym: Calcitonin salmon,Salmon calcitonin
Target: CGRP Receptor
Olcegepant
T12293L
Synonym: BIBN-4096,BIBN 4096BS
Target: CGRP Receptor
Rimegepant
T4610
Synonym: BMS 927711,BMS-927711,BMS927711,BHV-3000
Target: CGRP Receptor
MK-3207 Hydrochloride
T6590
Synonym: MK-3207 HCl
Target: CGRP Receptor
HCGRP-(8-37) acetate
TP1134L
Synonym: HCGRP-(8-37) acetate (119911-68-1 free base)
Target: CGRP Receptor
Galcanezumab
T76682
Synonym: LY 2951742
Target: CGRP Receptor
Erenumab
T76874
Synonym: AMG-334
Target: CGRP Receptor
Adrenomedullin (AM) (22-52), human acetate
TP1257L
Synonym: Adrenomedullin (AM) (22-52), human acetate（159899-65-7 Free base）
Target: CGRP Receptor
Telcagepant
T16093
Synonym: MK-0974
Target: Others
Olcegepant hydrochloride
T12293
Synonym: BIBN-4096 hydrochloride,BIBN4096BS hydrochloride
Target: Others
MK-8825
T70820
Synonym:
Target:
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat
T76363
Synonym:
Target:
Vazegepant
T38734
Synonym: Zavegepant,BHV-3500
Target:
BMS-694153
T30537
Synonym: BMS694153,BMS 694153
Target:
DD04107
T71246
Synonym:
Target:
HTL22562
T39522
Synonym:
Target:
(3R,5R,6S)-Atogepant
T73703
Synonym:
Target:
BI-44370
T26796
Synonym:
Target:
Fremanezumab
T76680
Synonym:
Target:
Adrenotensin (human)
T76473
Synonym:
Target:
MK-3207
T21558
Synonym:
Target:
Rimegepant sulfate hydrate
T70837
Synonym:
Target:
Eptinezumab
T76678
Synonym:
Target:
Cizolirtine citrate
T27025
Synonym: E-4018,E4018,E 4018
Target:
Amylin, amide, rat
TP1232
Synonym: Amylin (rat)
Target:
CRSP-1
TP2049
Synonym:
Target:
AC 187 TFA
T75934
Synonym:
Target:
Cyclo(L-Phe-L-Val)
T37476
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TP2167 β-CGRP, human acetate β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate CGRP Receptor
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP...
T21581L AC 187 Acetate AC 187 Acetate (151804-77-2 Free base) Amylin Receptor
AC 187 Acetate is a potent antagonist of amylin receptor .AC 187 shows more selective for amylin receptor than calcitonin and CGRP receptors.

Natural Products

β-CGRP, human acetate
TP2167
Synonym: β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate
Target: CGRP Receptor
AC 187 Acetate
T21581L
Synonym: AC 187 Acetate (151804-77-2 Free base)
Target: Amylin Receptor

Recombinant Proteins

Species：
Human (10)
Mouse (1)
Expression System：
HEK293 Cells (8)
E. coli (3)
Tag：
C-His (2)
C-hFc (2)
C-6xHis (1)
C-mFc (1)
N-10xHis-SUMO, C-Myc (1)
N-GST (1)
Tag Free (1)
hFc (1)
mFc (1)
Cat No. Product Name Species Expression System
TMPK-00678 CALCA/CGRP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a...
TMPY-04120 Procalcitonin/CALCA Protein, Human, Recombinant (mFc) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1.
TMPY-00066 Procalcitonin/CALCA Protein, Human, Recombinant (His) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1.
TMPH-01025 CALCA Protein, Human, Recombinant (GST) Human E. coli
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevate...
TMPY-03963 CALCB Protein, Human, Recombinant (mFc) Human HEK293 Cells
CALCB, also known as CGPR and calcitonin 2, belongs to the calcitonin family. CALCB is a calcitonin (CT) peptide which may play a role in the mediation of human inflammatory diseases. It is highly expressed in the skin, ...
TMPY-01466 S100A12 Protein, Human, Recombinant Human E. coli
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that...
TMPY-00371 STC1 Protein, Human, Recombinant (His) Human HEK293 Cells
Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has...
TMPY-03280 RAMP3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concent...
TMPY-02839 Adrenomedullin Protein, Human, Recombinant (hFc) Human HEK293 Cells
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the ca...
TMPJ-00362 MMP-2 Protein, Human, Recombinant (His) Human HEK293 Cells
72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metallo...
TMPH-01282 ELAVL4 Protein, Human, Recombinant (His & Myc & SUMO) Human E. coli
RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in th...
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