cd38 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14913	CD38 inhibitor 1		CD38
	CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.		CD38
T79732	CD38 inhibitor 3		CD38
	CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD+ content and Nrf2 expression. In a Pus1 -/- mouse model of ...		CD38
T61681	CD38 inhibitor 2
	CD38 inhibitor 2 is a potent CD38 inhibitor ( IC 50 = 0.01 ~ 0.1 μΜ).
T9918	Daratumumab		Others
	Daratumumab is a human monoclonal antibody that targets CD38 a cell surface protein that is overexpressed on multiple myeloma MM) cells.		Others
TN1895	Luteolinidin chloride		CD38
	Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.		CD38
T24920	UCD38B HCl	UCD38B hydrochloride,UCD 38 B hydrochloride,UCD-38-B HCl,UCD-38-B Hydrochloride,UCD 38 B HCl
	UCD38B HCl is a cell-permeable intracellular uPA inhibitor that acts by killing proliferative and non-proliferative high-grade glioma cells by programmed necrosis.
T69940	NCD38
	NCD38 is a potent, selective LSD1 inhibitor.
T78577	NCD38 TFA		Histone Demethylase
	NCD38 TFA serves as a selective inhibitor of LSD1 [1] [2].		Histone Demethylase
T61933	MK-0159		CD38
	MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury.		CD38
T60099	RBN013209		CD38
	RBN013209 is a potent CD38 inhibitor. RBN013209 is useful in the treatment of cancer.		CD38
T38951	Isatuximab	SAR-650984,hu38SB19,Isatuximab-irfc	Apoptosis , CD38
	Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system and is a highly expressed protein in multiple myeloma. Isatuximab has ...		Apoptosis , CD38
T77006	Felzartamab	TJ-202,MOR-03087,MOR-202	CD38
	Felzartamab(MOR-202) is a human-targeted monoclonal antibody to CD38 for the study of multiple myeloma and advanced antibody-mediated rejection of allogeneic kidney transplants.		CD38
TN1513	Clitorin		PKC , Antifection
	Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential.		PKC , Antifection
T38730	Ara-F-NAD+
	Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.
T77084	Mezagitamab
	Mezagitamab (TAK-079), an IgG1λ anti-CD38 monoclonal antibody, functions by depleting tumor cells that express CD38 through both antibody and complement-dependent cytotoxicity. It shows potential for use in the treatment...
T82440	Erzotabart		CD38
	Erzotabart, an IgG1-kappa monoclonal antibody targeting CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) in Homo sapiens, exhibits antineoplastic activity [1].		CD38
T37475	Cyclic ADP-Ribose (ammonium salt)	cADP-Ribose,cADPR,Cyclic ADP-Ribose (ammonium salt)
	Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types.[1],[2],[3],[4],[5] This second mes...
T77091	Modakafusp alfa
	Modakafusp alfa (TAK-573) is a humanized anti-CD38 IgG4 monoclonal antibody, with 2 attenuated IFNα2b molecules fused to it. This compound is researched for potential use in treating multiple myeloma [1].
T74032	Ara-F-NAD+ sodium
	Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].
T13907	Sulfo-ara-F-NMN	CZ-48	Others
	Sulfo-ara-F-NMN is an analogue of nicotinamide mononucleotide (NMN) with cellular permeability. Sulfo-ara-F-NMN was selective to activate SARM1 and inhibited CD38 with an IC50 of about 10 μM. Activation by Sulfo-ara-F-NM...		Others