20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22450 | Tyrphostin B44, (+) enantiomer | EGFR | |
Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer. | |||
T69984 | Ticalopride | 5-HT Receptor | |
Ticalopride is a 5-HT3 receptor agonist used in the treatment of digestive disorders, orofacial disorders, otorhinolaryngologic disorders, and may be used in the study of bulimia nervosa, gastroesophageal reflux, and irr... | |||
T2542 | Prucalopride | R-93877 | 5-HT Receptor |
Prucalopride (R-93877) is a selective, high-affinity 5-HT4A/4B receptor agonist (Ki: 2.5/8 nM). It has >290-fold selectivity for 5-HT4A/4B receptor than other 5-HT receptor subtypes. | |||
TN2256 | Taccalonolide B | Microtubule Associated | |
Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM. | |||
T40437L | Caloxin 2A1 acetate | Proton pump | |
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate. | |||
T6958 | Prucalopride Succinate | R-108512,Resolor Succinate | 5-HT Receptor |
Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively. | |||
TN2254 | Taccalonolide A | Apoptosis , Microtubule Associated | |
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these ... | |||
T75621 | Secalonic acid D | ||
Secalonic acid D, a toxic compound effective against tumor cells, is derived from the metabolites of Aspergillus aculeatus. It operates by activating GSK3-β and degrading β-catenin, consequently down-regulating c-Myc exp... | |||
T76558 | Onvitrelin ucalontide | ||
Onvitrelin ucalontide ([Phor18-LHRH (338613)]) is a luteinizing hormone-releasing hormone (LHRH) analogue possessing antineoplastic properties, characterized by the peptide sequence KFAKFAKKFAKFAKKFAKQHWSYGLRPG. It demon... | |||
T30696 | Calonyctin A-2b | DC-2b | |
Calonyctin A-2b is one of two components of calonyctin A. | |||
T124889 | Isocalolongic acid | ||
Isocalolongic acid is a useful organic compound for research related to life sciences. The catalog number is T124889 and the CAS number is 40737-92-6. | |||
T124691 | Calopocarpin | ||
Calopocarpin is a useful organic compound for research related to life sciences. The catalog number is T124691 and the CAS number is 53802-77-0. | |||
T30697 | Calonyctin A-2d | DC-2d | |
Calonyctin A-2d is one of two components of calonyctin. | |||
TN2255 | Taccalonolide AJ | Others | |
Taccalonolide AJ is a microtubule stabilizer; it has excellent and highly persistent antitumor efficacy when administered directly to the tumor, suggesting that the lack of antitumor efficacy seen with systemic administr... | |||
T35923 | Caloxin 2A1 TFA | ||
Caloxin 2A1 TFA is a peptide inhibitor specifically targeting the extracellular plasma membrane Ca2+-ATPase (PMCA), without influencing the basal activities of Mg2+-ATPase or Na+-K+-ATPase[1]. | |||
T80247 | Caloxin 3A1 | Calcium Channel | |
Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps. Specifically, it inhibits plasma membrane calcium pumps (PMCAs) without ... | |||
T82789 | Caloxin 1B1 | ||
Caloxin 1B1, a bioactive peptide, exhibits selective inhibition of PMCA extracellularly by binding preferentially to the extracellular domain 1 of PMCA4 over PMCA1. Identified through a screening process for its high-aff... | |||
T124792 | Cyclocalopin A | ||
Cyclocalopin A is a useful organic compound for research related to life sciences and the catalog number is T124792. | |||
T124052 | Calophymembranside B | ||
Calophymembranside B is a useful organic compound for research related to life sciences. The catalog number is T124052 and the CAS number is 869285-60-9. | |||
T38564 | Taccalonolide C | ||
Taccalonolides C is an anti-cancer agent. |