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Search Result

Search Results for " beta-lactamase "

Targets

Antibacterial

44

Compounds

15

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T19206 β-Lactamase-IN-1 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1 Antibacterial
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.
T35427 β-Lactamase-IN-2 Antibacterial
β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects.
T38476 Metallo β-lactamase ligand 1 Antibacterial
Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.
T14979 Clavulanate lithium Clavulanic acid lithium Antibacterial
Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.
T38956 β-Lactamase-IN-5
β-Lactamase-IN-5, a β-lactamase inhibitor isolated from compound 720, holds significant potential for studying bacterial infections.
T38955 β-Lactamase-IN-4
β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.
T39865 β-Lactamase-IN-6
β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity.
T1631 Sulbactam CP45899 Antibacterial , Antibiotic
Sulbactam (CP45899) is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabol...
T15047 Dacisteine N,S-Diacetyl-L-cysteine Others
Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).
T0234 Methicillin sodium salt Methicillin sodium,Meticillin sodium Antibacterial , Antibiotic
Methicillin sodium salt is the sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity.
T1031 Cloxacillin sodium monohydrate Cloxacillin Sodium,Bactopen Antibacterial , Antibiotic
Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
T5570 Cephalothin Cephalotin acid Antibacterial , Antibiotic
Cephalothin is a beta-lactam antibiotic, inhibits class C β-lactamase AmpC (Ki: 0.32 μM).
T1143 Carbenicillin disodium BRL-2064,Sodium carbenicillin Cell wall , Antibacterial , Antibiotic
Carbenicillin disodium (BRL-2064) is a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.
T1405 Cefditoren pivoxil ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl Antibacterial , Antibiotic
Cefditoren pivoxil (ME 1207) is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity.
T6268 Ceftiofur hydrochloride Ceftiofur HCl,U-67279A,Excenel hydrochloride Antibacterial , Antibiotic
Ceftiofur hydrochloride (U-67279A) is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity.
T19860 Clavulanic Acid BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151 Antibacterial , Antifungal
Clavulanic Acid(RX-10100), a major beta-lactam antibiotic produced by the organism Streptomyces claveris, is a potent bacterial beta-lactamase inhibitor used in the study of infections caused by bacteria. Clavulanic Acid...
T0868 Cefepime Dihydrochloride Monohydrate Cefepime HCl Antibacterial , Antibiotic , Antifection
Cefepime Dihydrochloride Monohydrate (Cefepime HCl) is the hydrochloride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad...
T1224 Cefuroxime sodium Anaptivan,Cefuroxime sodium salt,Biociclin Antibacterial , Antibiotic
Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium (Cefuroxime...
T1063 Ticarcillin disodium Ticarpen,Ticarcillin disodium salt Antibacterial , Antibiotic
Ticarcillin disodium (Ticarpen) is the disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action...
T26906 Brobactam
Brobactam is a beta lactamase inhibitor with antibacterial activity.
T25355 Durlobactam
Durlobactam is a drug candidate for beta-lactamase inhibitor.
T12604 Xeruborbactam QPX7728 Others
QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.
T69300 AVE-1330A free acid
AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor.
T28670 SB 204070 hydrochloride SB 204070 HCl
SB 204070 hydrochloride is an inhibitor of beta-lactamase, it is isolated from Spondias mombin.
T69999 Nacubactam monohydrate
Nacubactam monohydrate is a beta-lactamase inhibitor used for bacterial infections.
T69299 AVE-1330A sodium
AVE-1330A sodium is a beta-Lactamase inhibitor.
T71613 MK-8712
MK-8712 is a monobactam beta-lactamase inhibitor.
T28669 SB 202742 SB202742,SB-202742
SB 202742 is an inhibitor of beta-lactamase, it is isolated from Spondias mombin.
T69272 AM-112
AM-112 is an Oxapenem compound which possesses potent beta-lactamase-inhibitory properties.
TMIH-0530 Sulbactam-d2
Sulbactam-d2 is a deuterated compound of Sulbactam. Sulbactam has a CAS number of 68373-14-8. Sulbactam is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase...
T27386 FR-295389 FR-295389 Free Base,FR295389
FR-295389 is a cephalosporin. FR-295389 shows effective antibacterial activity against metallo-beta-lactamase (MBL)-producers in vitro.
T39287 Ledaborbactam
Iedaborbactam, as a beta-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections.
T73438 MK-3402
MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .
T75391 Penicillinase
Penicillinase is a beta-lactamase. beta-lactamase enzymes inactivate beta-lactam antibiotics by hydrolyzing the peptide bond of the characteristic four-membered beta-lactam ring rendering the antibiotic ineffective [1] .
T22433 Sulopenem CP-70429 Others
Sulopenem, an orally active, potent inhibitor of beta-lactamase, is a parenteral penem antibiotic with broad-spectrum activities against Gram-negative and Gram-positive bacteria.
T21163 Cloxacillin Sodium BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt
Cloxacillin Sodium, a chlorinated derivative of Oxacillin, is a semi-synthetic antibiotic. Cloxacillin is used for the treatment of infections caused by species of staphylococci which produce beta-lactamase.
T12524 Potassium clavulanate cellulose Potassium clavulanate:cellulose (1:1) Others
Potassium clavulanate cellulose is a mixture of potassium clavulanate and cellulose, is an inhibitor of beta-lactamase.
T21384 Dicloxacillin Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen
Dicloxacillin (INN), a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins...
T1190L Cefmenoxime A-50912,A 50912,A50912,AB 50912
Cefmenoxime is a cephalosporin antibiotic administered intravenously or intramuscularly. It is an effective inhibitor of Enterobacteriaceae and is resistant to beta-lactamase-initiated hydrolysis. It is active against mo...
T1023 Cefoxitin sodium Cenomycin,MK-306,Betacef,Merxin Antibacterial , Antibiotic
Cefoxitin sodium (Betacef) is a semisynthetic cephamycin antibiotic resistant to beta-lactamase.
T73668 Sanfetrinem sodium
Sanfetrinem sodium (GV104326), a beta-lactamase-stable antibiotic, exhibits broad-spectrum activity against both gram-positive and gram-negative bacteria [1].
T72261 Metallo-β-lactamase-IN-9
Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1].
T68938 Cefmenoxime sodium
Cefmenoxime sodium is the ssalt form of Cefmenoxime (free base), a cephalosporin antibiotic administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms. ...
T70621 Cefditoren Pivoxil HCl
Cefditoren Pivoxil is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil is a prodrug that is rapidly hydrolyzed by intest...

Compounds

β-Lactamase-IN-1
T19206
Synonym: 4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1
Target: Antibacterial
β-Lactamase-IN-2
T35427
Synonym:
Target: Antibacterial
Metallo β-lactamase ligand 1
T38476
Synonym:
Target: Antibacterial
Clavulanate lithium
T14979
Synonym: Clavulanic acid lithium
Target: Antibacterial
β-Lactamase-IN-5
T38956
Synonym:
Target:
β-Lactamase-IN-4
T38955
Synonym:
Target:
β-Lactamase-IN-6
T39865
Synonym:
Target:
Sulbactam
T1631
Synonym: CP45899
Target: Antibacterial, Antibiotic
Dacisteine
T15047
Synonym: N,S-Diacetyl-L-cysteine
Target: Others
Methicillin sodium salt
T0234
Synonym: Methicillin sodium,Meticillin sodium
Target: Antibacterial, Antibiotic
Cloxacillin sodium monohydrate
T1031
Synonym: Cloxacillin Sodium,Bactopen
Target: Antibacterial, Antibiotic
Cephalothin
T5570
Synonym: Cephalotin acid
Target: Antibacterial, Antibiotic
Carbenicillin disodium
T1143
Synonym: BRL-2064,Sodium carbenicillin
Target: Cell wall, Antibacterial, Antibiotic
Cefditoren pivoxil
T1405
Synonym: ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl
Target: Antibacterial, Antibiotic
Ceftiofur hydrochloride
T6268
Synonym: Ceftiofur HCl,U-67279A,Excenel hydrochloride
Target: Antibacterial, Antibiotic
Clavulanic Acid
T19860
Synonym: BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151
Target: Antibacterial, Antifungal
Cefepime Dihydrochloride Monohydrate
T0868
Synonym: Cefepime HCl
Target: Antibacterial, Antibiotic, Antifection
Cefuroxime sodium
T1224
Synonym: Anaptivan,Cefuroxime sodium salt,Biociclin
Target: Antibacterial, Antibiotic
Ticarcillin disodium
T1063
Synonym: Ticarpen,Ticarcillin disodium salt
Target: Antibacterial, Antibiotic
Brobactam
T26906
Synonym:
Target:
Durlobactam
T25355
Synonym:
Target:
Xeruborbactam
T12604
Synonym: QPX7728
Target: Others
AVE-1330A free acid
T69300
Synonym:
Target:
SB 204070 hydrochloride
T28670
Synonym: SB 204070 HCl
Target:
Nacubactam monohydrate
T69999
Synonym:
Target:
AVE-1330A sodium
T69299
Synonym:
Target:
MK-8712
T71613
Synonym:
Target:
SB 202742
T28669
Synonym: SB202742,SB-202742
Target:
AM-112
T69272
Synonym:
Target:
Sulbactam-d2
TMIH-0530
Synonym:
Target:
FR-295389
T27386
Synonym: FR-295389 Free Base,FR295389
Target:
Ledaborbactam
T39287
Synonym:
Target:
MK-3402
T73438
Synonym:
Target:
Penicillinase
T75391
Synonym:
Target:
Sulopenem
T22433
Synonym: CP-70429
Target: Others
Cloxacillin Sodium
T21163
Synonym: BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt
Target:
Potassium clavulanate cellulose
T12524
Synonym: Potassium clavulanate:cellulose (1:1)
Target: Others
Dicloxacillin
T21384
Synonym: Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen
Target:
Cefmenoxime
T1190L
Synonym: A-50912,A 50912,A50912,AB 50912
Target:
Cefoxitin sodium
T1023
Synonym: Cenomycin,MK-306,Betacef,Merxin
Target: Antibacterial, Antibiotic
Sanfetrinem sodium
T73668
Synonym:
Target:
Metallo-β-lactamase-IN-9
T72261
Synonym:
Target:
Cefmenoxime sodium
T68938
Synonym:
Target:
Cefditoren Pivoxil HCl
T70621
Synonym:
Target:

Recombinant Proteins

Species：
E. coli (6)
Human (2)
Pseudomonas aeruginosa (2)
Acinetobacter baumannii (1)
Klebsiella pneumoniae (1)
Salmonella typhimurium (1)
Serratia marcescens (1)
Streptomyces clavuligerus (1)
Expression System：
E. coli (13)
P. pastoris (Yeast) (2)
Tag：
N-6xHis-SUMO (6)
N-6xHis (3)
His (2)
C-6xHis (1)
N-10xHis, C-Myc (1)
N-GST (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPH-00588 Beta-lactamase Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins.
TMPH-03165 Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Pseudomonas aeruginosa E. coli
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735.
TMPH-03164 Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Pseudomonas aeruginosa E. coli
Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight...
TMPH-00584 Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) E. coli E. coli
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-00585 Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His) E. coli P. pastoris (Yeast)
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-03474 Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant Salmonella typhimurium E. coli
Has cefotaxime-hydrolyzing activity. Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28.4 kDa and the accession number is P...
TMPH-00586 Beta-lactamase TEM Protein, E. coli, Recombinant (His) E. coli P. pastoris (Yeast)
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPH-00587 Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO) E. coli E. coli
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4...
TMPH-00019 BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) Acinetobacter baumannii E. coli
BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 22.0 kDa. Accession number: F8UNN7
TMPJ-01157 LACTB2 Protein, Human, Recombinant (GST) Human E. coli
β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is ex...
TMPH-03602 BLIP Protein, S. clavuligerus, Recombinant (His & SUMO) Streptomyces clavuligerus E. coli
Inhibits a wide variety of beta lactamases. BLIP Protein, S. clavuligerus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.5 kDa and the acce...
TMPH-02373 Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) Klebsiella pneumoniae E. coli
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinol...
TMPH-03488 Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) Serratia marcescens E. coli
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant ...
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His) Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an...
TMPY-02447 Shiga toxin II subunit B Protein, E. coli, Recombinant (His) E. coli E. coli
E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic grou...
Beta-lactamase Protein, E. coli, Recombinant (His & SUMO)
TMPH-00588
Species: E. coli
Expression System: E. coli
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
TMPH-03165
Species: Pseudomonas aeruginosa
Expression System: E. coli
Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
TMPH-03164
Species: Pseudomonas aeruginosa
Expression System: E. coli
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)
TMPH-00584
Species: E. coli
Expression System: E. coli
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)
TMPH-00585
Species: E. coli
Expression System: P. pastoris (Yeast)
Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant
TMPH-03474
Species: Salmonella typhimurium
Expression System: E. coli
Beta-lactamase TEM Protein, E. coli, Recombinant (His)
TMPH-00586
Species: E. coli
Expression System: P. pastoris (Yeast)
Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)
TMPH-00587
Species: E. coli
Expression System: E. coli
BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO)
TMPH-00019
Species: Acinetobacter baumannii
Expression System: E. coli
LACTB2 Protein, Human, Recombinant (GST)
TMPJ-01157
Species: Human
Expression System: E. coli
BLIP Protein, S. clavuligerus, Recombinant (His & SUMO)
TMPH-03602
Species: Streptomyces clavuligerus
Expression System: E. coli
Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)
TMPH-02373
Species: Klebsiella pneumoniae
Expression System: E. coli
Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)
TMPH-03488
Species: Serratia marcescens
Expression System: E. coli
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
TMPY-02288
Species: Human
Expression System: E. coli
Shiga toxin II subunit B Protein, E. coli, Recombinant (His)
TMPY-02447
Species: E. coli
Expression System: E. coli
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