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Dacisteine

Name: Dacisteine
Brand: TargetMol
SKU: T15047
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15047Cas No. 18725-37-6

Alias N,S-Diacetyl-L-cysteine

Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 1000 μM.

Dacisteine

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Purity: 99.57%

Catalog No. T15047Alias N,S-Diacetyl-L-cysteineCas No. 18725-37-6

Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 1000 μM.

Pack Size	Price	Availability
25 mg	$41	In Stock
50 mg	$67	In Stock
100 mg	$98	In Stock
200 mg	$148	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.57%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 1000 μM.
Targets&IC50	NDM1:1000 μM
In vivo	Dacisteine can be used for research on the treatment of cardiovascular and cerebrovascular diseases caused by platelet aggregation[1].
Synonyms	N,S-Diacetyl-L-cysteine

Chemical Properties

Molecular Weight	205.23
Formula	C₇H₁₁NO₄S
Cas No.	18725-37-6
Smiles	CC(=O)N[C@@H](CSC(C)=O)C(O)=O
Relative Density.	1.314 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1218.15 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (24.36 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8726 mL	24.3629 mL	48.7258 mL	243.6291 mL
5 mM	0.9745 mL	4.8726 mL	9.7452 mL	48.7258 mL
10 mM	0.4873 mL	2.4363 mL	4.8726 mL	24.3629 mL
20 mM	0.2436 mL	1.2181 mL	2.4363 mL	12.1815 mL
50 mM	0.0975 mL	0.4873 mL	0.9745 mL	4.8726 mL
100 mM	0.0487 mL	0.2436 mL	0.4873 mL	2.4363 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc