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Clavulanate lithium

Catalog No. T14979 CAS 61177-44-4

Synonyms: Clavulanic acid lithium

Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.

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Clavulanate lithium, CAS 61177-44-4

Pack Size	Availability	Price/USD
5 mg	In stock	$ 39.00
10 mg	In stock	$ 64.00
25 mg	In stock	$ 113.00
50 mg	In stock	$ 172.00
100 mg	In stock	$ 255.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.51%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Clavulanate lithium (Clavulanic acid lithium) is an inhibitor of β-lactamase.
In vitro	Combination of Clavulanate lithium with beta-lactam antibiotics prevents microbial lactamases from inactivating antibiotics, but when administered alone has weak antimicrobial activity against most organisms, causing relatively slow growth inhibition[1].

Synonyms	Clavulanic acid lithium
Molecular Weight	205.09
Formula	C8H8LiNO5
CAS No.	61177-44-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 44.8 mg/mL (218.44 mM), Sonification is recommended.

DMSO: 4.5 mg/mL (21.84 mM), Sonification and heating to 80℃ are recommended.

References and Literature

1. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852–857. 2. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Drug Repurposing Compound Library Covalent Inhibitor Library Bioactive Compound Library Approved Drug Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library Anti-Bacterial Compound Library Clinical Compound Library Beta-Lactam Compound Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Clavulanate lithium 61177-44-4 Microbiology/Virology Antibacterial Clavulanate beta-lactam Inhibitor Amoxycillin inhibit Antibiotic beta-lactamase Bacterial β-lactamase Clavulanic acid lithium inhibitor

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