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Search Results for " brd9 "

20

Compounds

Cat No. Product Name Synonyms Targets
T6859 I-BRD9 GSK602 Epigenetic Reader Domain
I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.
T13915L PROTAC BRD9-binding moiety 1 hydrochloride PROTAC BRD9-binding moiety 1 hydrochloride (2097512-23-5 free base) Others
PROTAC BRD9-binding moiety 1 hydrochloride binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.
T12560 PROTAC BRD9 Degrader-1 Epigenetic Reader Domain
PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
T13915 PROTAC BRD9-binding moiety 1 Epigenetic Reader Domain
PROTAC BRD9-binding moiety 1 that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.
T77975 PROTAC BRD9 Degrader-6 Epigenetic Reader Domain
PROTAC BRD9 Degrader-6, with an IC50 value of 0.13 nM, is a potent degrader of BRD9 suitable for research on BAF complex-related disorders [1].
T82821 BRD9 Degrader-1 Epigenetic Reader Domain
BRD9 Degrader-1 functions as a BRD9 degrader, demonstrating micromolar binding affinity towards BRD9 and nanomolar affinity for the ternary complex involving BRD9 and VCB [1].
T81384 PROTAC BRD9 Degrader-3 PROTACs
PROTAC BRD9 Degrader-3 is a bifunctional degrader targeting BRD9, utilized in cancer research.
T81383 PROTAC BRD9 Degrader-5 PROTACs
PROTAC BRD9 Degrader-5 is a proteolysis targeting chimera (PROTAC) designed for the specific degradation of Bromodomain-containing protein 9 (BRD9).
T81385 PROTAC BRD9 Degrader-2 PROTACs
PROTAC BRD9 Degrader-2 is a bifunctional compound designed for the targeted degradation of BRD9 in cancer research applications.
T77936 PROTAC BRD9 Degrader-4 PROTACs
PROTAC BRD9 Degrader-4 is a bifunctional degrader targeting BRD9, designed for cancer research applications.
T81382 PROTAC BRD9 Degrader-7 PROTACs
PROTAC BRD9 Degrader-7 is a selective and orally active BRD9 degrader with a DC50 of 1.02 nM and demonstrates superior pharmacokinetics, evidenced by a Cmax of 3436.95 ng/mL [1].
T74256 PROTAC BRD9-binding moiety 5
PROTAC BRD9-binding moiety 5, a selective binder of BRD9 with an IC50 value of 4.20 μM, is utilized in PROTAC synthesis and exhibits antiproliferative activity against cancer cells [1].
T15441 GSK8573 Epigenetic Reader Domain
GSK8573 is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 (Kd of 1.04 μM).
T31221 DBRD9 dBRD-9,dBRD 9 PROTACs
dBRD9 is a PROTAC. dBRD9 is a double-acting molecule, partially containing Bromodomain-containing protein 9 (BRD9), ligand that recruits the cereblon E3 ubiquitin ligase. Ligand that recruits the cereblon E3 ubiquitin li...
T31221L DBRD9 HCl dBRD9 HCl(2170679-45-3 Free base) Epigenetic Reader Domain
dBRD9 HCl is a PROTAC composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide . dBRD9 HCl is a potent and selective degrader of BRD9 (IC50 = 56.6 nM in MOLM-13 cells). dBRD9 HCl do...
T8342 BRD9876 Others , Kinesin , Microtubule Associated
BRD9876 is a selective inhibitor of MM1S growth.
T7378 BRD9539 Histone Methyltransferase
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM
T35480 DBRD9-A dBRD9-A
Potent BRD9 degrader. Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xeno...
T14780 BRD9185 Dehydrogenase
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
T30584 BRD9092 BRD 9092,BRD-9092
BRD9092 is an enhancer of reactive oxygen species that are nontoxic or cause genotype-selective cell death.
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TargetMol