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Cat No. | Product Name | Synonyms | Targets |
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T38622 | Bcl-xL antagonist 2 | BCL | |
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic l... | |||
T14376 | AZD4320 | BCL | |
AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively. | |||
T70008 | Bomedemstat ditosylate | ||
Bomedemstat, also known as IMG-7289, is a lysine-specific histone demethylase 1 (LSD1) inhibitor with antineoplastic activity. Bomedemstat may be useful in the treatment of acute myeloid leukaemia, myelodysplastic syndro... | |||
T29172 | YD277 | YD 277,YD-277 | |
YD277 is a small molecule derived from ML264, a KLF5 inhibitor that elicits cytotoxic effects in colon cancer cell lines. YD277 significantly induced G1 cell cycle arrest and apoptosis in MDA-MB-231 and MDA-MB-468 TNBC c... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6S0052 | Chelerythrine | Toddalin,Broussonpapyrine,Cheleritrine | Apoptosis , BCL , PKC , Autophagy |
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera... |
Cat No. | Product Name | Species | Expression System |
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TMPY-02431 | BCL-XL Protein, Human, Recombinant (His) | Human | E. coli |
BCL-XL Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 25.2 kDa and the accession number is A0A0S2Z3C5. | |||
TMPH-02650 | FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory... |