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Search Results for " atpases "

17

Compounds

Cat No. Product Name Synonyms Targets
T14965 Ciliobrevin D ATPase , Hedgehog/Smoothened
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity ...
T9882 RUVBL1/2 ATPase-IN-1 Others
RUVBL1/2 ATPase-IN-1 is an effective RUVBL1/2 ATPase inhibitor with IC50 values of 6.0 and 7.7 μM, respectively. RUVBL1/2 ATPase-IN-1 can be used in cancer disease studies.
T2686 Esomeprazole Magnesium (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium ATPase , Proton pump
Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...
T17030 Tegoprazan ATPase , Proton pump
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastric acid secretion and motility (IC50: ranging from 0.29-0.5...
T2686L Esomeprazole Sodium (S)-Omeprazole sodium ATPase , Proton pump
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...
T4897 Inosine-5'-triphosphate trisodium salt ITP,Inosine 5'-triphosphate trisodium salt Others , Endogenous Metabolite
Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra...
T8386 Esomeprazole Magnesium trihydrate (S)-Omeprazole magnesium trihydrate Proton pump
Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...
T21550 Blebbistatin (±)-Blebbistatin ATPase , Myosin
Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell jun...
T22598 Bafilomycin C1 Others
vacuolar H+-ATPases (V-ATPases) inhibitor
T6038 (-)-Blebbistatin (S)-(-)-Blebbistatin ATPase , Myosin
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 μM.
T36116 Concanamycin B
Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late...
T28626 Rutamycin Oligomycin D,A272,A 272,A-272
Rutamycin is a macrolide antibiotic of the oligomycin group obtained from Streptomyces rutgersensis. It inhibits various ATPases and uncouples oxidative phosphorylation from electron transport.
T76374 SPAI-1
SPAI-1, a peptide isolated from porcine duodenum, serves as a specific inhibitor to monovalent cation transporting ATPases, effectively inhibiting Na+, K+-ATPase and H+, K+-ATPase while stimulating Mg2+-ATPase in vitro [...
T38441 Manzamine A hydrochloride
Manzamine A hydrochloride is an orally active beta-carboline alkaloid that exhibits specific inhibitory effects on GSK-3β (IC50 = 10.2 μM) and CDK-5 (IC50 = 1.5 μM). Additionally, it targets vacuolar ATPases, leading to ...
T75585 Naja Mossambica Venom
Naja Mossambica Venom (Mozambique Spitting Cobra Venom) is a snake venom derived from Naja Mossambica, exhibiting antifungal activity against Candida species. Additionally, extracts from Naja Mossambica Venom, including ...
T36335 (S)-nitro-Blebbistatin
(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in...
T36400 Para-amino-Blebbistatin
para-amino-Blebbistatin is a more water-soluble form of (S)-4'-nitro-blebbistatin , which is a more stable and less phototoxic form of (-)-blebbistatin .1,2,3 (-)-Blebbistatin is a selective cell-permeable inhibitor of n...
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