as-85 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39861	AS-85
	AS-85, a potent inhibitor of ASH1L histone methyltransferase (IC50 = 0.6 μM), exhibits anti-leukemic activity by strongly binding to the ASH1L SET domain (Kd = 0.78 μM).
T1409	Methocarbamol	Lumirelax,Metocarbamol,AHR 85,Robaxin	Sodium Channel , Carbonic Anhydrase
	Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful musc...		Sodium Channel , Carbonic Anhydrase
T67956	Litoxetine		5-HT Receptor
	Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently r...		5-HT Receptor
T70601	MDK03855
	MDK03855, also known as A2AR antagonist 19, is an adenosine A2A receptor (A2AR) antagonist. MDK03855 has CAS#1454903-85-5. The last five digit of CAS# was used for name.
T18594	HG-7-85-01-Decyclopropane	PROTAC ABL binding moiety 3	Others
	Decyclopropane, also known as HG-7-85-01, is a chemical compound with ABL inhibitor properties. It binds to the IAP ligand through a linker, resulting in the formation of SNIPER [1].		Others
TN4287	Isoelemicin		Others
	Isoelemicin is a natural product of Erythrina, Fabaceae. The catalog number is TN4287 and the CAS number is 5273-85-8. Isoelemicin can be used as a reference standard.		Others
TN4907	Rengyol		Others
	Rengyol is a natural product of Forsythia, Oleaceae. The catalog number is TN4907 and the CAS number is 93675-85-5. Rengyol can be used as a reference standard.		Others
T38653	HG-7-85-01
	HG-7-85-01 is a type II ATP competitive inhibitor targeting wild-type and gatekeeper mutations forms of Bcr-Abl, PDGFRα, Kit, and Src kinases. It effectively inhibits T315I mutant Bcr-Abl kinase, as well as KDR and RET k...
TN4881	Quinamine		Others
	Quinamine is a natural product of Remijia, Rubiaceae. The catalog number is TN4881 and the CAS number is 464-85-7. Quinamine can be used as a reference standard.		Others
TN5032	Sitosteryl palmitate		Others
	Sitosteryl palmitate is a natural product of Astilbe, Saxifragaceae. The catalog number is TN5032 and the CAS number is 2308-85-2. Sitosteryl palmitate can be used as a reference standard.		Others
TN3997	Erythrinin C		Others
	Erythrinin C is a natural product of Erythrina, Fabaceae. The catalog number is TN3997 and the CAS number is 63807-85-2. Erythrinin C can be used as a reference standard.		Others
T80248	PKCε (85-92)		PKC
	PKCε (85-92) is a biologically active peptide that functions as a specific activator of ε-PKC and induces MARCKS phosphorylation in wild-type cells, but does not affect MARCKS phosphorylation in cells derived from knocko...		PKC
T83065	Antifungal agent 85
	Compound 24f, an antifungal agent also known as 'Antifungal agent 85,' demonstrates potent antibacterial properties, exhibiting minimum inhibitory concentration (MIC) values ranging from 2.5 to 10 μM against diverse Gram...
TN3036	4-Hydroxy-3-(3-methyl-2-butenoyl)-5-(3-methyl-2-butenyl)benzoic acid		Others
	4-Hydroxy-3-(3-methyl-2-butenoyl)-5-(3-methyl-2-butenyl)benzoic acid is a natural product of Piper, Piperaceae. The catalog number is TN3036 and the CAS number is 155051-85-7. 4-Hydroxy-3-(3-methyl-2-butenoyl)-5-(3-methy...		Others
T37644	Bengamide B
	Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cell...
T9654	JNJ-54717793
	JNJ-54717793 is an orally active, brain-penetrating compound that acts as a selective and high-affinity antagonist of the orexin-1 receptor (OX1R) with a plasma EC50 of 85 ng/mL. It demonstrates K_i values of 16 nM for h...
T36112	Clopidogrel Carboxylic Acid (hydrochloride)
	Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex ...
T35663	Cortistatin-29 (rat) (trifluoroacetate salt)
	Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cort...
T38172	RO 5263397 hydrochloride
	Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhib...
T14216	AMG 837		Others
	AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex...		Others