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Search Results for " apx "

Targets

10

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10354 APX-115 Ewha-18278 NADPH-oxidase
APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.
T10353 APX-115 free base Ewha-18278 free base NADPH-oxidase , NADPH
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid...
T61355 APX2039 APX-2039,APX 2039 Antifungal
APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent an...
T23749 APX001 APX 001,APX-001
APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.
T70731 Odalasvir
Odalasvir is a novel NS5A inhibitor for the treatment of hepatitis C.
T70730 Oxycodegol phosphate
Oxycodegol phosphate is a mu-opioid agonist used in the treatment of Moderate to Severe Chronic Low Back Pain
T70733 APX2009
APX2009 is a second-generation APE1/Ref-1 redox-specific inhibitor. APX2009 significantly reduces NFkB transcriptional activity, survivin mRNA, and survivin protein levels. APX2009 decreases prostate cancer cell prolifer...
T70732 APX2014
APX2014 is a novel potent and specific Ref-1 inhibitor, blocking in vitro cell proliferation and activating apoptosis via PARP cleavage.
T6823 E3330 HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
T11314 Fosmanogepix APX001,E1211 Others
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02433 APE1/APEX1 Protein, Human, Recombinant (His) Human E. coli
The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diest...
TMPJ-00464 APE Protein, Human, Recombinant Human E. coli
Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete re...
TMPH-00096 APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana E. coli
APX2, cytosolic Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is Q1PER6.
TargetMol